Effect of Timing of a Post-exercise Oral Glucose Tolerance Test on Glycaemic Control.
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Postprandial glucose concentration area under the curve
研究概览
简要总结
Postprandial glycaemic control is an important risk factor for the development of type 2 diabetes, cardiovascular disease and all-cause mortality.
Previous research has demonstrated that exercise performed in the postprandial state paradoxically results in a deterioration in glucose tolerance in the immediate post-exercise period (Gonzalez et a. 2013; Gonzalez and Stevenson 2013). This study aims to assess the timecourse of this post-exercise effect.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Normal weight (18-25 kg/m2)
- •Physically active (>or= 3 times per week)
排除标准
- •Contraindications to exercise
- •Food intolerances
- •Food allergies
研究组 & 干预措施
Rest
Breakfast followed by a rest period prior to OGTT.
干预措施: Rest (Behavioral)
Exercise-immediate
Breakfast followed by exercise and an immediate OGTT
干预措施: Exercise (Behavioral)
Exercise-delay
Breakfast followed by exercise and a delayed (1 h) OGTT.
干预措施: Exercise (Behavioral)
Exercise-delay
Breakfast followed by exercise and a delayed (1 h) OGTT.
干预措施: Delay (Behavioral)
结局指标
主要结局
Postprandial glucose concentration area under the curve
时间窗: 90 min
Blood glucose concentrations will be sampled every 15 min following an oral glucose tolerance test.
次要结局
- Postprandial insulin concentration area under the curve(90 min)
研究者
Javier Gonzalez, PhD
Research Fellow
Northumbria University