Exercise Timing and Postprandial Glycemia in Type 2 Diabetes
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 13
- Primary Endpoint
- glucose concentrations
Study Overview
Brief Summary
With many medications we prescribe them relative to time of day or a meal. This study established if pre dinner vs post dinner exercise was more effective at altering post dinner glucose and triglyceride levels vs no exercise at all.
Detailed Description
All participants completed three trials in a random order in which they consumed a standardized dinner meal with 1) no RE (NoRE), 2) pre-dinner RE (RE→M), and 3) post-dinner RE beginning 45 min after dinner (M→RE). Diet was standardized during the day of testing. Participants reported to the lab for testing sometime between 3 - 5:30 p.m. and upon arrival a venous catheter was inserted into a forearm vein. Frequent blood sampling, indirect calorimetry measurements, and subjective well-being measurements ensued for ~5.75 h while the participants were in the lab.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Other
- Masking
- None
Eligibility Criteria
- Ages
- 25 Years to 55 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Obese ( body mass index 30-45 kg/m2)
- •Physician diagnosed with type 2 diabetes receiving standard medical care
- •Non-smokers
- •Pregnancy
- •Lactating mothers
Exclusion Criteria
- •Surgical weight loss
- •Orthopedic limitations to exercise
- •Weight loss in the previous 3 months
Outcomes
Primary Outcomes
glucose concentrations
Time Frame: Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h
Secondary Outcomes
- triglyceride concentrations(Blood samples were taken every 5-10 min during the first 3.7 h of testing and every 30 min during the last 2 h)
Investigators
Jill Kanaley
professor
University of Missouri-Columbia