Examination of clinical effect of green coffee bean extract on healthy subjects.
- Conditions
- Healthy subjects
- Registration Number
- JPRN-UMIN000048584
- Lead Sponsor
- Teikyo Heisei University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 63
Not provided
1. Those who are currently receiving medication due to some kind of breath. 2. Those who currently have a habit of taking or applying drugs. 3. Persons with a history of mental illness or current medical history. 4. Treatment for stroke, subarachnoid hemorrhage, cerebral infarction, cerebral hemorrhage, cerebral contusion Head trauma Those who have experience of hospitalization surgery. 5. Persons with a history of hypertension, dyslipidemia, diabetes, or current medical history. 6. Persons with a history or current medical history of heart failure, renal failure, hepatitis B, hepatitis C. 7. Persons with a history or current medical history of serious disorders such as liver, kidney, heart, lungs, and blood. 8. As a general rule, those who have a history of comorbidities in the digestive system. 9. Persons with a BMI (kg / m2) of 30 or more. 10. Those who drink more than 60g / day on average in terms of alcohol per day. 11. Those who smoke an average of 21 or more cigarettes per day. 12. Those with severe anemia. 13. Those who may have allergic symptoms to the test product, or those who may have serious allergic symptoms to other foods and medicines. 14. Currently, and within the past 3 months, those who have a habit of continuing to take functional foods, health foods, and supplements that appeal to similar effects to the test product, and who plan to take them during the study period. Person. 15. Those who have a habit of continuing to take health foods and supplements containing test-containing ingredients, and who plan to take them during the test period, now and within the past 3 months. 16. Those who may change their lifestyle during the examination period. 17. Those who are currently participating in other human clinical trials, or those who have not been heard for 3 months after participating in other human clinical trials. 18. Others who are judged by the investigator to be inappropriate for this study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Praimary outcomes is Bourdon' seher Durchstreichte. A Bourdon' seher Durchstreichte is performed before the experiment and after 4 weeks, 8 weeks, and 12 weeks.
- Secondary Outcome Measures
Name Time Method 1.Mini Mental State Examination-Japanese 2.WHOQOL26 3.Uchida Kleperin test 4.Cerebral blood flow in Uchida Kleperin 5.Blood BDNF 6.Blood alpha-synuclein 7.Blood eicosanoyl-5-hydroxytryptamide 8.Blood chlorogenic acid 9.Red blood cells, Hb, hematocrit, platelets, average red blood cell volume, Mean corpuscular hemoglobin Hb amount, mean red blood cell Hb concentration, reticulocyte, white blood cell)