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Exercise therapy and cognitive behavioural therapy in Postpoliomyelitis Syndrome: effects on fatigue, activities and quality of life.

Completed
Conditions
Postpoliomyelitis Syndrome, neuromuscular disease, exercise therapy, cognitive behavioral therapy, fatigue, activities of daily living, quality of life.
Registration Number
NL-OMON26099
Lead Sponsor
Academic Medical Center (AMC), Department of Rehabilitation
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
81
Inclusion Criteria

1. Diagnosis of PPS according to the criteria of March and Dimes i.e.

a. Prior paralytic poliomyelitis with evidence of motor neuron loss, as confirmed by history of the acute paralytic illness, signs of residual weakness and atrophy of muscles on neurologic examination, and signs of denervation on electromyography (EMG).

Exclusion Criteria

1. Cognitive impairment

2. Insufficient mastery of the Dutch language

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Primary outcome measures are:<br /><br>- QoL (SF-36) <br /><br>- Limitations in activities (Sickness Impact Profile, domains: mobility range, mobility control, social behaviour)<br /><br>- Fatigue (Checklist Individual Strength, domain: fatigue)
Secondary Outcome Measures
NameTimeMethod
Secondary outcome measures are:<br /><br>- Pain<br /><br>- Psychological well-being<br /><br>- Physical activity level in daily life<br /><br>- Perceived participation<br /><br>- Illness cognitions<br /><br>- Coping <br /><br>- Perceived control or self-efficacy<br /><br>- Cost effectiveness<br /><br /><br>Additional secondary outcome measures for the exercise therapy group:<br /><br>- Cardiorespiratory fitness<br /><br>- Neuromuscular capacity<br /><br>- Functional capacity<br />
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