A Pilot Study Investigating Patient Function/Fitness and Psychosocial Health in Patients With Non-Small Cell Lung Cancer
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Smoking
- Sponsor
- Wake Forest University Health Sciences
- Locations
- 1
- Primary Endpoint
- Patient function/fitness
- Status
- Withdrawn
- Last Updated
- 7 years ago
Overview
Brief Summary
This pilot trial studies patient function/fitness and psychosocial health in improving health-related quality of life and decreasing treatment-related toxicity in patients with stage I-IV non-small cell lung cancer. Studying function/fitness and psychosocial health may help doctors improve conventional therapy in patients with non-small cell lung cancer.
Detailed Description
PRIMARY OBJECTIVES: I. To determine the correlation of patient-reported health-related quality of life (HRQOL) outcomes with clinical/treatment variables as well as a panel of both function/fitness and psychosocial health assessments in non-small cell lung cancer (NSCLC). SECONDARY OBJECTIVES: I. To investigate the panel of function/fitness and psychosocial health assessments with patient's smoking history/status as a predictor for treatment related toxicity. TERTIARY OBJECTIVES: I. The documentation of the NSCLC lung population from this prospective combined with others. OUTLINE: Patients scheduled for surgery, radiation therapy, or chemotherapy complete the European Organization for Research and Treatment of Cancer (EORTC) quality of life questionnaire (QLQ)-core 30 (C30) and QLQ-Lung Cancer 13 (LC13) in addition to psychosocial health and smoking status questions from baseline up to 2 weeks prior to the start of treatment, 5-6 weeks after treatment begins, and 5-6 months from the start of treatment. During the same time points, patients also undergo function/fitness assessments including standard health measurements, short physical performance battery (SPPB), 6 minute walk test (6MWT), and a grip strength test. After completion of study treatment, patients are followed up every 3-6 months.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Newly diagnosed lung cancer
Exclusion Criteria
- •Previous or active lung cancer treatment at the time of registration
Outcomes
Primary Outcomes
Patient function/fitness
Time Frame: Up to 6 months
Assessed by performance-based measures.
Patient well-being
Time Frame: Up to 6 months
Assessed by psychosocial health questions.