Changes in the sense of smell and taste in patients undergoing chemotherapy for head and neck malignancies
- Conditions
- C10.8C32.8Overlapping lesion of oropharynxOverlapping lesion of larynx
- Registration Number
- DRKS00003361
- Lead Sponsor
- Hals-, Nasen-, Ohrenheilklinik der Universitätsmedizin Mainz
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 33
Inclusion Criteria
Head and neck squamous cell carcinoma, informed consent
Exclusion Criteria
Olfactory disorders as a result of a chronic rhinosinusitis, head trauma, neurodegenerative disease, inability to give informed consent
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie olfactory and gustatory dysfunction in head and neck cancer patients receiving platinum-based chemotherapy?
How does cisplatin-induced neurotoxicity compare to standard-of-care treatments in affecting chemosensory function in oropharyngeal and laryngeal malignancies?
Are specific biomarkers like EGFR or TP53 mutations associated with chemosensory changes in head and neck cancer patients undergoing chemotherapy?
What are the most common adverse events related to taste and smell alterations in head and neck cancer chemotherapy and how are they managed?
What combination therapies or targeted agents are being explored to mitigate chemosensory dysfunction in head and neck cancer patients alongside conventional chemotherapy?