Prospective Observation Cohort Study of Malignant Lymphoma Patients
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Lymphoma
- Sponsor
- Samsung Medical Center
- Enrollment
- 1358
- Locations
- 1
- Primary Endpoint
- All cause mortality
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
The purpose of this study is to establish a model which can predict the treatment outcome and the risk of treatment-related morbidity in patients with lymphoma.
Detailed Description
Although the cure rate of lymphoma has been increased due to the development of newer effective drugs, a substantial portion of patients is still suffered from relapse. Furthermore, the treatment-related morbidity is another factor which can make the treatment outcome worse in patients with lymphoma, especially elderly patients. Thus, this study is going to assess factors which may affect the treatment outcome and the risk of treatment-related morbidity. 1.Biologic factors associated with the aggressiveness of lymphoma * molecular markers in serum, cytogenetic markers 2.Factors associated with the risk of treatment-related morbidity * comorbidity, nutrition status, performance status, quality of life at diagnosis
Investigators
Won Seog Kim
Professor
Samsung Medical Center
Eligibility Criteria
Inclusion Criteria
- •Patients who were diagnosed as lymphoma
- •Over 19 years old
- •Patients who agreed the enrollment of study
- •Informed consent for sampling
Exclusion Criteria
- •Patients who do not want to join the study
Outcomes
Primary Outcomes
All cause mortality
Time Frame: 5 years
Disease and non-disease-related mortality including treatment-related death
Secondary Outcomes
- Biomarker development(5 years)
- Rate of occurrence of toxicity(2 years from the start of the 1st therapy)
- Treatment response(1 year)
- Quality of life(5 years)