iver stiffness in septic shock patients
Not Applicable
- Conditions
- Health Condition 1: I958- Other hypotension
- Registration Number
- CTRI/2023/06/053891
- Lead Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adult patients with septic shock, on vasopressor for at least 24 hours
AND
Documentation of normal LFT and normal echogenicity of liver on ultrasound during current illness (before inclusion)
Exclusion Criteria
1.Age <18 years
2.Onset of septic shock >7 days
3.Known liver disease (viral hepatitis, non-alcoholic fatty liver disease, alcoholic liver
4.disease, autoimmune, cholestasis and genetic liver disease, focal liver disease)
5.Congestive heart failure
6.BMI >35
7.Pregnancy
8.Intraabdominal hypertension
9.Recent history of abdominal trauma or surgery
10.Technical difficulties (breathe holding/unable to transport)
11.Patients who do not provide written consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the prevalence & severity of increased liver stiffness in patients with septic shockTimepoint: Within 7 days of septic shock
- Secondary Outcome Measures
Name Time Method To study the change in liver stiffness, 4-6 weeks after stopping vasopressorsTimepoint: Within 6 weeks after ICU discharge