Effect of convalescent plasma therapy on intensive care unit (ICU) deaths from COVID-19 in Suriname

Not Applicable

Completed

• Conditions: COVID-19 (SARS-CoV-2 infection); Infections and Infestations

• Registration Number: ISRCTN18304314
• Lead Sponsor: Academic Hospital Paramaribo

Brief Summary

2023 Results article in https://doi.org/10.1128/mbio.03379-22 (added 12/06/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-01-10
• Study Start: 2021-04-13
• Last Update Posted: 26 June 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

1. Polymerase chain reaction (PCR) confirmed COVID-19 disease
2. Aged >18 years
3. Written informed consent to participate in the study from the patient, or legal patient representative if the patient is unconscious (spouse or 1st-degree family member, and if absent 2nd-degree family member or acquaintance)
4. Admittance to the ICU due to progressive respiratory failure ranging between severe and life-threatening ARDS based on the Berlin classification
5. Requiring non-invasive ventilation

Exclusion Criteria

1. Requiring invasive ventilation
2. A no ICU admission” or no invasive ventilation” restriction in place at the time of screening for the study
3. Admitted to the COVID-19 ward but asymptomatic, admitted due to the national admission policy, or mild SARS-CoV2

Study & Design

• Study Type: Interventional
• Study Design: Not specified