iver fibrosis associated with Fontan circulation - evaluation of diagnostic methods and potential risk factors

Recruiting

• Conditions: Fontan circulation; Q23.4; Q22.4; Q20.4; Q22.6; Hypoplastic left heart syndrome; Congenital tricuspid stenosis; Double inlet ventricle; Hypoplastic right heart syndrome

• Registration Number: DRKS00024083
• Lead Sponsor: niversitätsklinikum Schleswig-Holstein Campus Kiel

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-19
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Fontan circulation

Exclusion Criteria

Contraindications for MRI, ferromagnetic implants, pacemaker

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluation of non-invasive diagnostics methods for characterisation of Fontan associated liver fibrosis.<br><br>Shearwave elastography<br>non-contrast enhanced MRI (T1 and T2 mapping, diffusion weighted imaging, 4D flow, spectroscopy)<br>Laboratory parameters<br><br>Comparison with routine diagnostics

Secondary Outcome Measures

Name	Time	Method
Evaluation of risk factors for liver fibrosis