Effects of an Individualized Training Program on Severity Markers of Obstructives Sleep Apnea/Hypopnea Syndrome (OSAS)

Not Applicable

Completed

• Conditions: Exercise Training Therapy; Sleep Apnea, Obstructive
• Interventions: Other: training and educational program; Other: educational program

• Registration Number: NCT01256307
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

There are two types of treatments depending on the severity of Obstructive Sleep Apnea/Hypopnea Syndrome (OSAS): - for the treatment of severe (AHI\> 30/h), the standard treatment is Continuous Positive Airway Pressure (CPAP). If it proved effective in reducing excessive daytime sleepiness and associated cardiovascular risk, compliance of patients 4 years of treatment falls below 70%. - Treatment of moderate (AHI between 15 and 30/h), lifestyle measures, the bracing of mandibular advancement and / or possibly the head and neck surgery can be proposed. These treatments include side effects and their effectiveness is very controversial.Il therefore seemed interesting to test the impact of physical activity through a standardized training program to re personal effort on the development and improvement of OSAS patients with a sedentary moderate to severe OSAS (AHI between 15 and 40 / h) The main assumption is that the ESR could eventually delay the initiation of treatment with CPAP in severe OSAS or an alternative therapeutic relevance in the moderate OSAS and severe in patients who can not tolerate conventional treatment(CSF). The main objective of this biomedical research is to evaluate the effects of a program of REE in ambulatory index of hourly apneas / hypopneas (AHI = marker of severity of OSAS) .- objectives specify 2AIR effects of REE on the quality of sleep (TxSLP) and daytime symptoms (EDS objective fatigue) on the one hand and the other on the metabolism (OV, SM, IR) and markers of LCR (inflammation, oxidative stress , endothelial function).

Detailed Description

Not available

Study Timeline

• Study Start: 2009-11
• Study First Submitted: 2010-10-28
• Study First Submitted QC: 2010-12-06
• Study First Posted: 2010-12-08
• Primary Completion: 2013-07
• Study Completion: 2013-07
• Status Verified: 2014-12
• Last Update Submitted: 2014-12-03
• Last Update Posted: 2014-12-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

• Presence of an OSAS
• Apnea Hypopnea Index between 15 and 45/h
• Sedentary subjects (Voorips Activity questionnaire)
• IMC<40

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
training group	training and educational program	training and educational program
control group	educational program	-

Primary Outcome Measures

Name	Time	Method
change delta index of hourly apneas/hypopneas at eight weeks after inclusion	8 weeks

Trial Locations

Locations (1)

Montpellier University Hospital; 🇫🇷 Montpellier, France