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MASSACHUSETTS GENERAL HOSPITAL

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1811-01-01

Employees: -

Market Cap: -

Website: http://www.massgeneral.org/international

Clinical Trials

PDAC-PATHWAYS: A Digital Informational and Supportive Care App for Patients Initiating Neoadjuvant Therapy for Pancreatic Ductal Adenocarcinoma

Not Applicable

Not yet recruiting

Conditions: PDAC - Pancreatic Ductal Adenocarcinoma

First Posted Date: 2025-07-02

Last Posted Date: 2025-07-02

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 50

Registration Number: NCT07047807

Locations: 🇺🇸
Massachusetts General HospitaL, Boston, Massachusetts, United States

Trial of Oral Digoxin in Individuals With Amyotrophic Lateral Sclerosis (ALS)

Not Applicable

Recruiting

Conditions: ALS (Amyotrophic Lateral Sclerosis)

Interventions: Drug: Digoxin

First Posted Date: 2025-07-02

Last Posted Date: 2025-07-02

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 40

Registration Number: NCT07047209

Locations: 🇺🇸
MGH, Boston, Massachusetts, United States

Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories

Not Applicable

Not yet recruiting

Conditions: Preeclampsia
Gestational Hypertension

Interventions: Drug: Placebo tablet to match spironolactone
Drug: spironolactone 25 mg orally once daily

First Posted Date: 2025-06-27

Last Posted Date: 2025-06-29

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 204

Registration Number: NCT07041281

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
🇺🇸
University of Pittsburgh Magee-Womens Hospital, Pittsburgh, Pennsylvania, United States

Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

Not Applicable

Recruiting

Conditions: Crohn Disease
Inflammatory Bowel Diseases
Healthy

First Posted Date: 2025-06-24

Last Posted Date: 2025-06-24

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 10

Registration Number: NCT07033208

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Mezigdomide and Talquetamab in Relapsed and Refractory Multiple Myeloma

Phase 1

Not yet recruiting

Conditions: Relapsed Refractory Multiple Myeloma (RRMM)

Interventions: Drug: Talquetamab
Drug: Mezigdomide
Drug: Dexamethasone

First Posted Date: 2025-06-24

Last Posted Date: 2025-06-26

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 25

Registration Number: NCT07032714

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
🇺🇸
Dana-Farber Cancer Institute, Boston, Massachusetts, United States

Risk Informed Obesity Care Plan Pilot

Conditions: Childhood Obesity

First Posted Date: 2025-06-19

Last Posted Date: 2025-06-19

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 720

Registration Number: NCT07028814

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes

Recruiting

Conditions: Anesthesia
Sedation
Surgery
Surgery Scheduled
Fasting Before Operation
Monitored Anesthesia Care
Surgery, Day
Procedure
Aspiration; Gastric Contents, Anesthesia

First Posted Date: 2025-06-15

Last Posted Date: 2025-06-15

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 1200000

Registration Number: NCT07022951

Locations: 🇺🇸
Mass General Brigham, Boston, Massachusetts, United States

Addressing Emotional Distress in Dyads of Persons With a Young Onset Dementia (YOD) and Their Care-partners

Not Applicable

Not yet recruiting

Conditions: Young Onset Dementia

First Posted Date: 2025-06-12

Last Posted Date: 2025-06-12

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 388

Registration Number: NCT07018726

Locations: 🇺🇸
Massachusetts General Hospital (MGH), Boston, Massachusetts, United States

Pomalidomide for the Treatment of Bleeding in Hereditary Hemorrhagic Telangiectasia Longitudinal Assessment Study

Active, not recruiting

Conditions: Hereditary Hemorrhagic Telangiectasia (HHT)

First Posted Date: 2025-06-12

Last Posted Date: 2025-06-12

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 62

Registration Number: NCT07018401

Locations: 🇺🇸
University of California-San Diego, San Diego, California, United States
🇺🇸
University of California-San Francisco, San Francisco, California, United States
🇺🇸
University of Florida, Gainesville, Florida, United States

and more 8 locations

A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship

Not Applicable

Not yet recruiting

Conditions: Lymphoma

First Posted Date: 2025-06-10

Last Posted Date: 2025-06-10

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 254

Registration Number: NCT07013435

Locations: 🇺🇸
Mass General Hospital, Boston, Massachusetts, United States

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