Ionized Magnesium Balance During Hemodialysis Session

• Conditions: Chronic Kidney Diseases
• Interventions: Biological: Lymphatic drainage; Biological: Total and ionized magnesium; Biological: Total and ionized calcium

• Registration Number: NCT05337436
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

Aim of this study is to evaluate in a population of chronic kidney disease patients on dialysis (Stage 5D) the balance of total and ionized magnesium according to different types of dialysate used in clinical practice (acetate + Mg 0.50 or 0.75 mM vs citrate + Mg 0.50 ou 0.75 mM)

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-04
• Study Start: 2022-04-01
• Study First Submitted: 2022-04-13
• Study First Submitted QC: 2022-04-13
• Study First Posted: 2022-04-20
• Last Update Submitted: 2022-04-20
• Last Update Posted: 2022-04-27
• Primary Completion: 2022-07-01
• Study Completion: 2022-12-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
All patients receive conventional dialysis treatment at enrollment	Lymphatic drainage	All patients receive conventional dialysis treatment at enrollment
All patients receive conventional dialysis treatment at enrollment	Total and ionized magnesium	All patients receive conventional dialysis treatment at enrollment
All patients receive conventional dialysis treatment at enrollment	Total and ionized calcium	All patients receive conventional dialysis treatment at enrollment

Primary Outcome Measures

Name	Time	Method
Comparison of ionized magnesium levels before and after dialysis session	day 1	Comparison of ionized magnesium levels before and after dialysis session

Secondary Outcome Measures

Name	Time	Method
Comparison of total magnesium levels before and after dialysis session	day 1	Comparison of total magnesium levels before and after dialysis session
Comparison of ionized calcium levels before and after dialysis session	day 1	Comparison of ionized calcium levels before and after dialysis session
Comparison of total calcium levels before and after dialysis session	day 1	Comparison of total calcium levels before and after dialysis session
Per-dialytic balance of ionized magnesium according to predialysis level	day 1	Per-dialytic balance of ionized magnesium according to predialysis level
Per-dialytic balance of total magnesium according to predialysis level	day 1	Per-dialytic balance of total magnesium according to predialysis level
Per-dialytic balance of ionized calcium according to predialysis level	day 1	Per-dialytic balance of ionized calcium according to predialysis level
Per-dialytic balance of total calcium according to predialysis level	day 1	Per-dialytic balance of total calcium according to predialysis level

Trial Locations

Locations (1)

Uhmontpellier; 🇫🇷 Montpellier, France