Evaluation of Meibomian Gland Dysfunction Before and After Cataract Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- the change of parameters associated with dry eye syndrome
研究概览
简要总结
This study will compare cataract patients before and after phacoemulsification. Evaluations will be performed before and 1 and 3 months following cataract surgery, including parameters of dry eye syndrome and MGD. Dry eye syndrome parameters included TBUT, Schirmer's test type I, Oxford staining score, and the Ocular Surface Disease Index (OSDI) Questionnaire. MGD parameters consisted of lipid layer thickness (LLT), lid margin abnormality, meibum quality, meibum expressibility, MG orifice obstruction, MGD stage, and MG dropout.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with cataract surgery planning with phacoemulsification and intraocular lens implantation with or without mild dry eye syndrome
排除标准
- •the previous use of eye drops, except artificial tears within 3 months before cataract surgery
- •a history of previous ocular surgery or trauma
- •the presence of ocular comorbidities such as glaucoma, uveitis, cystoid macular edema, and any surgical complications including rupture of the posterior capsule during cataract surgery.
研究组 & 干预措施
cataract patients
cataract patients undergoing phacoemulsification
干预措施: Lipiview 2 (Device)
结局指标
主要结局
the change of parameters associated with dry eye syndrome
时间窗: baseline and 1 month after POD(postoperative day)
Analysis the change of parameters associated with dry eye syndrome before and after cataract surgery measured by lipiview 2.
the change of parameters associated with meibomiangland dysfunction
时间窗: baseline and 1 month after POD(postoperative day)
Analysis the change of parameters associated with meibomiangland dysfunction before and after cataract surgery measured by lipiview 2.
次要结局
未报告次要终点