Impact of Augmenting Exercise Intensity vs. Frequency on Peak Work Rate
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Exercise Training
- Sponsor
- Brendon Gurd, PhD
- Enrollment
- 16
- Locations
- 1
- Primary Endpoint
- Peak work rate
- Last Updated
- 6 years ago
Overview
Brief Summary
The purpose of this study is to compare the impact of augmenting exercise intensity and augmenting exercise frequency on peak work rate. Participants will complete exercise tests and provide 8 skeletal muscle samples following a within-subjects randomized crossover design utilizing single-leg cycling. Both training periods will be 4 weeks long and skeletal muscle biopsies will be collected from both legs before and after each training period. All exercise sessions will be supervised, take place in the investigator's laboratory, and occur on stationary bikes.
Investigators
Brendon Gurd, PhD
Professor, School of Kinesiology & Health Studies, Queen's University
Queen's University
Eligibility Criteria
Inclusion Criteria
- •Recreational active (\<3 hours per week of aerobic exercise)
- •Willing to provide skeletal muscle biopsies
Exclusion Criteria
- •Cardiovascular or metabolic disease
- •Athletes or individuals exceeding 3 hours per week of aerobic exercise
Outcomes
Primary Outcomes
Peak work rate
Time Frame: Before exercise training on two days (~7 and 6 days before first training session; ~24 hours apart), and after exercise on two days (~48-96 hours after the last training session; ~24 hours apart)
Change in Highest work rate achieved (30s period) during incremental exercise tests
Secondary Outcomes
- Peak oxygen uptake(Before exercise training on two days (~7 and 6 days before first training session; ~24 hours apart), and after exercise on two days (~48-96 hours after the last training session; ~24 hours apart))
- Maximal citrate synthase activity(Before exercise training (~7 days before first training session), and after exercise training (~48-72 hours after the last training session))