MedPath

Exercise CMR in (p)LF-LG AS

Recruiting
Conditions
Aortic Stenosis, Severe
Registration Number
NCT06129799
Lead Sponsor
University of Göttingen
Brief Summary

Patient with paradoxical or conventional low-flow low-gradient aortic stenosis on echocardiographic assessment will undergo physiological exercise-stress CMR in addition to guideline recommended surveys prior to TAVR.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
100
Inclusion Criteria
  • paradoxical or conventional severe low-flow low-gradient aortic stenosis
Read More
Exclusion Criteria
  • CMR incapable device
  • unable to undergo 40 min scan (can not lie flat, claustrophobia)
  • renal insufficiency (eGFR <30 ml/min/1.73m²)
  • allergy against contrast agent
  • unable to exercise in supine position
Read More

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Composite of events: number of participants with cardiovascular death or heart failure hospitalisation12 months
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

University Hospital Goettingen

🇩🇪

Göttingen, Germany

© Copyright 2025. All Rights Reserved by MedPath