Cardiovascular Magnetic Resonance Real-time Exercise Stress Testing in Heart Failure With Preserved Ejection Fraction

University of Göttingen1 site in 1 country75 target enrollmentAugust 16, 2017

ConditionsDiastolic Heart Failure

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Diastolic Heart Failure
Sponsor: University of Göttingen
Enrollment: 75
Locations: 1
Primary Endpoint: Cardiovascular magnetic resonance imaging
Status: Completed
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Patients of the University Hospital Göttingen with echocardiographic signs for diastolic heart failure and indication for right heart catheterisation will undergo additional diagnostic testing with CMR including exercise stress for detailed evaluation of diastolic dysfunction and tissue characterisation correlating the results with well-established clinical standards.

Registry

clinicaltrials.gov

Start Date

August 16, 2017

End Date

September 1, 2020

Last Updated

5 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University of Göttingen

Responsible Party

Principal Investigator

Andreas Schuster

PD Dr. med

University of Göttingen

Eligibility Criteria

Inclusion Criteria

•adult patients with dyspnoea under stress, echocardiographic criteria for diastolic dysfunction (E/E'\>8) and clinical indication for right heart catheterisation

Exclusion Criteria

•arrhythmia (brady- or tachycardic)
•bronchial asthma (allergic)
•incompliant patient
•pacemaker, ICD, non MRI-capable devices
•inability to use the ergometer in the MRI
•haemodynamic relevant valvular heart disease
•pulmonary disease (vital capacity or forced expiratory flow \<80% of healthy control)
•angina pectoris
•post cardiac infarction
•anaemia (Hb \<12 g/dl)