NCT03260621已完成不适用
Cardiovascular Magnetic Resonance Real-time Exercise Stress Testing in Heart Failure With Preserved Ejection Fraction
University of Göttingen2 个研究点 分布在 1 个国家目标入组 75 人开始时间: 2017年8月16日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 75
- 试验地点
- 2
- 主要终点
- Cardiovascular magnetic resonance imaging
研究概览
简要总结
Patients of the University Hospital Göttingen with echocardiographic signs for diastolic heart failure and indication for right heart catheterisation will undergo additional diagnostic testing with CMR including exercise stress for detailed evaluation of diastolic dysfunction and tissue characterisation correlating the results with well-established clinical standards.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients with dyspnoea under stress, echocardiographic criteria for diastolic dysfunction (E/E'>8) and clinical indication for right heart catheterisation
排除标准
- •arrhythmia (brady- or tachycardic)
- •bronchial asthma (allergic)
- •incompliant patient
- •pacemaker, ICD, non MRI-capable devices
- •inability to use the ergometer in the MRI
- •haemodynamic relevant valvular heart disease
- •pulmonary disease (vital capacity or forced expiratory flow <80% of healthy control)
- •angina pectoris
- •post cardiac infarction
- •anaemia (Hb <12 g/dl)
- •uncontrollable hypertension (>150 mmHg systolic or >100 mmHg diastolic)
- •age <18 years
- •pregnancy
- •claustrophobia
- •renal insufficiency
- •allergic to gadolinium based contrast agents
结局指标
主要结局
Cardiovascular magnetic resonance imaging
时间窗: approx. 1 years
ventricular and atrial volumes
次要结局
未报告次要终点
研究者
Andreas Schuster
PD Dr. med
University of Göttingen
研究点 (2)
Loading locations...
相似试验
招募中
不适用
Diastolic Function Assessment With Cardiac Magnetic Resonance ImagingDiastolic DysfunctionNCT05438030Imperial College London37
尚未招募
不适用
Cardiovascular Magnetic resonance imaging and Echocardiography in Rheumatoid Arthritis - Patterns of cardiovascular dysfunction in patients with rheumatoid arthritis.- cardiovascular disease - rheumatoid arthritis - cardiac magnetic resonance imaging - echocardiography - cardiovasculaire ziekte - reumatoide artritis - cardiale MRI - echocardiografieNL-OMON21327Medisch Spectrum Twente, Enschede, The NetherlandsDepartment of Cardiology and Department of Rheumatology80
已完成
不适用
Magnetic Resonance Imaging of the Blood Vessels of the HeartHeart DiseaseNCT00001638National Heart, Lung, and Blood Institute (NHLBI)2,916
进行中（未招募）
不适用
The UHSM Cardiovascular Magnetic Resonance StudyCardiovascular DiseasesNCT02326324Manchester University NHS Foundation Trust10,000
招募中
不适用
Evaluation of Longterm Outcome of New York Heart Association Class III Heart Failure Patients Receiving Telemonitoring Using a Pulmonary Artery Pressure Sensor System (CardioMEMS)Chronic Heart FailureNCT03020043Johann Wolfgang Goethe University Hospital500