Effectiveness of ozone gel placed in gums of patients with gum disease.

Phase 3

Not yet recruiting

Conditions: Chronic periodontitis
Chronic periodontitis,

Registration Number: CTRI/2025/05/086087

Lead Sponsor: TPCTs Terna Dental College

Brief Summary: This is a randomized clinical split mouth study to evaluatethe clinical efficacy of sub-gingivally delivered ozone as an adjunct to scalingand root plaing in patients undergoing non-surgical treatment of chronicperiodontitis. It is a split-mouth study.

Study design :

Group 1 consisting of 15 sites with 4-7mm pockets, receivingozone as a local drug delivery agent along with scaling and root planning.

Group 2 consisting of 15 sites with 4-7mm pockets, receivingundergoing scaling and root planning alone.

The clinical parameters [ plaque index, gingival index,relative attachment loss, probing pocket depth , modified sulcular bleedingindex]will be evaluated at baseline, one month and three month period.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 15

Inclusion Criteria

1)Adult patients 2)Bilateral periodontal sites, presence of at least one site in each quadrant with a probing depth of 5-7mm 3)Absence of systemic disease.

Exclusion Criteria

Absence of dental implants 2) Use of bisphosphonates 12 months prior to entry in the study 3) Pregnant/ lactating women 4) Anti-cancer therapy.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the efficacy of Ozone Gel as an adjunct to scaling and root planing versus scaling and root planing alone for Non-surgical treatment of Chronic Periodontitis.	At baseline \| After 1 month \| After 3 months

Secondary Outcome Measures

Name	Time	Method

Trial Locations

Locations (1): Terna Dental College
🇮🇳
Thane, MAHARASHTRA, India
Terna Dental College
🇮🇳Thane, MAHARASHTRA, India
Dr Sanika Patil
Principal investigator
7420830981
drsanika99@gmail.com