TCTR20220928006
Completed
Not Applicable
FLT3 Gene Mutations among Acute Myeloid Leukemia patients in Northeast Thailand
/A0 sites65 target enrollmentSeptember 28, 2022
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- /A
- Enrollment
- 65
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
Frequencies of FLT3-ITD and TKD were found to be 16.9% (11/65) and 10.8% (7/65), respectively. The WBC and peripheral blast percentage of FLT3-ITD positive patients were statistically significantly higher than those of the FLT3-wild type patients, while the peripheral blast percentage of FLT3-TKD positive patients was significantly lower. No other clinical characteristics among FLT3 positive and FLT3-wild type patients were observed.DNA sequencing identified 4 FLT3-TKD mutations.
Investigators
Eligibility Criteria
Inclusion Criteria
- •all newly diagnosed AML patients between January 2020 and May 2021
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Not specified
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