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Clinical Trials/TCTR20220928006
TCTR20220928006
Completed
Not Applicable

FLT3 Gene Mutations among Acute Myeloid Leukemia patients in Northeast Thailand

/A0 sites65 target enrollmentSeptember 28, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
/A
Enrollment
65
Status
Completed
Last Updated
last year

Overview

Brief Summary

Frequencies of FLT3-ITD and TKD were found to be 16.9% (11/65) and 10.8% (7/65), respectively. The WBC and peripheral blast percentage of FLT3-ITD positive patients were statistically significantly higher than those of the FLT3-wild type patients, while the peripheral blast percentage of FLT3-TKD positive patients was significantly lower. No other clinical characteristics among FLT3 positive and FLT3-wild type patients were observed.DNA sequencing identified 4 FLT3-TKD mutations.

Registry
who.int
Start Date
September 28, 2022
End Date
May 31, 2021
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
/A

Eligibility Criteria

Inclusion Criteria

  • all newly diagnosed AML patients between January 2020 and May 2021

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Not specified

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