A NOVEL observational longiTudinal studY on patients with a diagnosis or suspected diagnosis of asthma and/or COPD to describe patient characteristics, treatment patterns and the burden of illness over time and to identify phenotypes and endotypes associated with differential outcomes that may support future development of personalised treatment strategies

Recruiting

• Conditions: Chronic bronchitis; emphysema; 10001708; 10038716

• Registration Number: NL-OMON55674
• Lead Sponsor: Astra Zeneca

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 140

Inclusion Criteria

· Diagnosis, or suspected diagnosis**, of asthma and/or COPD, according to
clinician's judgement
· Age >=12 years (note: in most countries it will only be feasible to include
patients aged >=18 years)
· Willing and able to sign written, informed consent (or having a responsible,
legally authorised representative acting on patient's behalf)
· Enrolment from an active clinical practice

Exclusion Criteria

· Patients who participated in any respiratory interventional trial during the
12 months prior to enrolment or at enrolment
· Patients who, in the opinion of the physician, are unlikely to complete 3
years of
follow-up, e.g. poor literacy, substance abuse, life-threatening co-morbidity
· Patients whose primary respiratory diagnosis (i.e. the condition causing most
of their respiratory symptoms) is not asthma or COPD (however, a co-diagnosis
of another respiratory disease such as bronchiectasis or interstitial lung
disease together with asthma or COPD will be accepted)
In addition, the following are considered criteria for exclusion from the
exploratory genetic research (donation of blood for DNA and RNA analysis)
· Previous allogeneic bone marrow transplant
· Non-leukocyte depleted whole blood transfusion within 120 days of the date of
the genetic sample collection

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified