Comparison of Dexmedetomidine and Dexmedetomidine-Ketamine combination efficacy as intranasal premedication in paediatric infraumbilical surgeries
- Conditions
- Medical and Surgical,
- Registration Number
- CTRI/2025/03/081696
- Lead Sponsor
- Dr Fehima Haris
- Brief Summary
This is a comparative observation study comparing effectiveness of intranasal dexmedetomidine 3mcg/kg with intranasal dexmedetomidine(2mcg/kg)-ketamine(2mg/kg) combination as a premedication in paediatric infraumbilical surgeries . While there has been much research on the individual effectiveness of dexmedetomidine and ketamine as paediatric premedication, there has been limited evidence on their combined efficacy . Our primary objective is to compare effectiveness of intranasal dexmedetomidine versus dexmedetomidine-ketamine combination as a premedication in terms of mask acceptance score in paediatric patients undergoing general anaesthesia for infraumbilical surgeries.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 144
Paediatric patients of age 1-6 years of either sex undergoing elective infraumbilical surgeries of ASA physical status I or II.
Known allergy to study drugs Cardiac arrhythmia or congenital heart disease Raised intracranial tension Children with mental retardation Intranasal mass or nasal bleeding.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the effectiveness of intranasal dexmedetomidine versus intranasal dexmedetomidine-ketamine combination as a premedication in terms of mask acceptance score in paediatric patients undergoing general anaesthesia for infraumbilical surgeries Mask acceptance score will be assessed at the time of induction that is 30 minutes after giving premedication
- Secondary Outcome Measures
Name Time Method To assess level of sedation using Ramsay sedation score To determine Child-parent separation score
Related Research Topics
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Trial Locations
- Locations (1)
Government medical college Kozhikode
🇮🇳Kozhikode, KERALA, India
Government medical college Kozhikode🇮🇳Kozhikode, KERALA, IndiaDr Fehima HarisPrincipal investigator9539833177fehimaharis04282@gmail.com