Comparison of efficacy of dexmedetomidine versus dexamethasone with levobupivacaine in caudal block for post operative analgesia

Completed

• Conditions: Persons encountering health services in other specified circumstances,

• Registration Number: CTRI/2021/03/032151
• Lead Sponsor: Jawaharlal Nehru medical college ajmer

Brief Summary

The aim of study will be  to compare the efficacy and safety of addition of dexmedetomidine versus dexamethasone to caudal 0.2% levobupivacaine on postoperative analgesia in paediatric patients undergoing infraumbilical surgeries

Primary objective  will be to assess duration of analgesia (from the time of caudal block to the time at which FLACC Pain score 4 or more)



Secondary objective will be to assess

1.postoperative sedation

2. Hemodynamic changes

3.Total number of doses of rescue analgesia in 24 hours

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-20
• Study Completion: 2021-12-31
• Last Update Posted: 2022-02-24

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• 1.patients between the age group of 1year and 8year of both sexes undergoing various infraumbilical surgeries 2.
• Patients belonging to ASA 1 and 2 grades 3.parental consent.

Exclusion Criteria

• 1.patients with known allergy to the study drugs 2.
• Suspected coagulopathy 3.
• Infection at site of caudal block 4.History of developmental delay and neurological diseases 5.
• Skeletal deformities in the caudal region 6.parental refusal.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcome of study will be assesment of Duration of analgesia (from the time of caudal injection to the time at which FLACC pain Pain score 4 or more)	Duration of study will be around 1year

Secondary Outcome Measures

Name	Time	Method
Secondary outcome of study will be assesment of 1.postoperative sedation	2. Hemodynamic changes

Trial Locations

Locations (1)

Jawaharlal nehru medical college and associated group of hospitals; 🇮🇳 Ajmer, RAJASTHAN, India

Jawaharlal nehru medical college and associated group of hospitals

🇮🇳Ajmer, RAJASTHAN, India

Dr LAXMI

Principal investigator

7073690374

laxmibishnoi129@gmail.com