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临床试验/NCT06054139
NCT06054139招募中不适用

Risk Factors for Refeeding Syndrome in the Surgical Intensive Care Unit

Samsun University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2023年6月9日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
60
试验地点
1
主要终点
Occurrence of Refeeding Syndrome

研究概览

简要总结

Refeeding Syndrome is a condition that occurs when patients who are undernourished or undernourished suddenly start overfeeding, causing electrolyte disturbances and vitamin deficiencies, resulting in neurological and cardiac problems. It may even result in death. It is aimed to prevent the development of Refeeding Syndrome with nutrition in accordance with the guidelines. The aim of this study is to determine the risk factors for Refeeding Syndrome in Intensive Care Unit (ICU).

详细描述

Nutritional support is an important part of treatment in intensive care patients. Especially existing comorbidities and developing acute problems before intensive care admission can cause serious malnutrition for patients. Refeeding syndrome is a serious, life-threatening condition accompanied by electrolyte and metabolic disorders as a result of rapid re-feeding following prolonged starvation or malnutrition. The condition may be accompanied by electrolyte disorders such as hypophosphatemia, hypokalemia and hypomagnesemia, as well as decrease in vitamin levels (especially vitamin B1), fluid imbalance and salt retention. The resulting imbalances can cause cardiac and neurological side effects, impaired organ functions and even death. The refeeding protocol should be individualized to each patient's clinical situation. In this study, although nutritional protocols in accordance with the guidelines are applied in patients with risk factors for the development of Refeeding Syndrome, whether Refeeding Syndrome develops and the facilitating factors will be investigated in ICU.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients are intensive care patients
  • Patients' age > 18 -

排除标准

  • Diabetic ketoacidosis
  • Other risk factors for hypophosphatemia (patients on continuous hemodialysis, hyperphosphatemia treatment, parathyroidectomy)
  • Patients with pre-study hypophosphatemia (< 0.65 mmol/L)
  • Patients with hyperparathyroidism
  • Terminal stage cancer patients
  • Patients with Glasgow Coma Scale ≤5
  • Patients with respiratory and metabolic alkalosis -

结局指标

主要结局

Occurrence of Refeeding Syndrome

时间窗: from june 9, 2023 to june 9, 2024

Occurrence of RFS:Within 72 hours after feeding serum phosphorus \< 0.0.87mmol/L, or from the baseline levels drop \> 0.16% or drop \> 30%;And (or) hypokalemia, hypomagnesemia, hypocalcemia and corresponding clinical symptoms

次要结局

未报告次要终点

研究者

发起方
Samsun University
申办方类型
Other
责任方
Principal Investigator
主要研究者

serife secgin

Specialist of Anaesthesiology and Reanimation Principle İnvestigator

Samsun University

研究点 (1)

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