Dynamic Changes in Some Facial Muscles After Superficial Versus Deep Hyaluronic Acid Injection: An Electromyographic Study
试验速览
- 阶段
- 早期 1 期
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- electrophysiological changes in some facial muscles
研究概览
简要总结
assess electrophysiological changes in some facial muscle dynamics following hyaluronic acid filler injection in superficial versus deep level of injection.
详细描述
Participants will be subjected to injection of cross-linked hyaluronic acid fillers on both sides of the face in 3 different regions: temples, cheeks and chins.
Each female will undergo:
-
Before injection:
-
Aesthetic facial clinical analysis.
-
Baseline quantitative surface electromyography.
-
Baseline digital photography.
-
Injection:
Each female will receive the injection in the particular facial region at superficial level to the muscle (subcutaneous) on one side and the same amount at deep level to the muscle (supraperiosteal) on the other side. 3. One week after injection:
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Age: 20-60 years.
- •Sex: females.
- •Areas eligible for injection: temples, cheeks and chin.
排除标准
- •Active infection near the site of injection.
- •Pregnant or lactating women.
- •Patients suffering from any neuromuscular disorders.
- •Known allergy/hypersensitivity to hyaluronic acid fillers.
- •History of botulinum toxin injection in the last 4 months.
- •History of injection of fillers in the last 2 years.
- •Patients receiving any muscle relaxants.
- •Coagulation disorder or anticoagulants therapy.
研究组 & 干预措施
deep injection of hyaluronic acid fillers
Each female will receive filler injection deep to the muscle (supraperiosteal) on one side of the face.
干预措施: hyaluronic acid filler injection (Drug)
superficial injection of hyaluronic acid fillers
Each female will receive filler injection at superficial level to the muscle (subcutaneous) on the contralateral side(same dose and same site).
干预措施: hyaluronic acid filler injection (Drug)
结局指标
主要结局
electrophysiological changes in some facial muscles
时间窗: one week
baseline and follow up quantitative surface electromyography
次要结局
未报告次要终点
研究者
marwa eldeeb
lecturer of dermatology
Alexandria University