Effect of oxygen on management of patients having brain surgery
Not Applicable
Completed
- Conditions
- Health Condition 1: null- neurosurgical patientsHealth Condition 2: G952- Other and unspecified cord compression
- Registration Number
- CTRI/2017/11/010499
- Lead Sponsor
- Dr Hemangi S karnik
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1) Patients undergoing neurosurgical procedures in supine or supine with head up position.
2) Patients needing invasive arterial access during surgery.
Exclusion Criteria
1) Patients with impaired pulmonary gas exchange (baseline hypercarbia,hypoxia).
2) Patients with dependence on oxygen supplementation or CPAP.
3) Patients with bronchial asthma/COPD.
4) Patients with chest trauma/ chest drain in situ.
5) Operated pneumonectomy or lobectomy in past.
6) Patients with abdominal distension /pregnancy/ascites/any other cause affecting breathing.
7) Any contraindication for nitrous oxide.
8) Patients requiring frequent changes in ventilatory strategies.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To ascertain if PaCO2_EtCO2 gradient changes with varying FiO2 concentration.Timepoint: August 2017
- Secondary Outcome Measures
Name Time Method to find correlation between FiO2 % and PaCO2-EtCO2 gradient,if any.Timepoint: June 2017