A randomised controlled trial of supplemental oxygen versus medical air in people with chronic obstructive pulmonary disease: Supplemental Oxygen in Pulmonary Rehabilitation Trial (SuppORT)
- Conditions
- People with COPD who experience oxygen desaturation during exerciseRespiratory - Chronic obstructive pulmonary disease
- Registration Number
- ACTRN12612000395831
- Lead Sponsor
- The University of Sydney
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 110
People will be eligible for inclusion if they:
a) have a medical diagnosis of COPD (forced expiratory volume in one second (FEV1) / forced vital capacity ratio of < 0.7; FEV1 between 20% to 80% predicted normal)
b) oxygen saturation < 90% during a 6MWT performed breathing room air.
People will be excluded if they:
a) are receiving long term oxygen therapy or have a resting partial pressure of oxygen in arterial blood (PaO2) on room air less than or equal to 55 mmHg or have a resting PaCO2 greater then 50mmHg.
b) have musculoskeletal, cardiovascular or neurological conditions likely to adversely affect performance during assessments or training.
c) have participated in supervised exercise training within the last 12 months.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Exercise capacity via endurance shuttle walk test time[Baseline, eight weeks, six months];Health-related quality of life via chronic respiratory disease questionnaire (CRDQ)[Baseline, eight weeks, six months]
- Secondary Outcome Measures
Name Time Method Dyspnea via the CRDQ dyspnea domain and the Dyspnoea-12 questionnaire[Baseline, eight weeks, six months];Physical activity level via the SenseWear Armband[Baseline, eight weeks, six months];Peak exercise capacity via the incremental shuttle walk test[Baseline, eight weeks, six months]