跳至主要内容
临床试验/NCT04248075
NCT04248075
Unknown
不适用

Effect of Sedatives on Perioperative Electroencephalogram in Elderly Patients Undergoing Spinal Anesthesia

SMG-SNU Boramae Medical Center0 个研究点目标入组 120 人2020年4月1日

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Effect of Sedatives
发起方
SMG-SNU Boramae Medical Center
入组人数
120
主要终点
EEG frequency bands (alpha, beta, theta, delta, and gamma waves) during spinal anesthesia
最后更新
6年前

概览

简要总结

In the present study, we observe perioperative findings of electroencephalogram in sedated and non-sedated elderly patients undergoing total knee arthroplasty under spinal anesthesia.

详细描述

In the present study, we observe perioperative findings of electroencephalogram in sedated and non-sedated elderly patients undergoing total knee arthroplasty under spinal anesthesia. Electroencephalogram is performed before, during, and 1 day after surgery. After the induction of anesthesia, sedation is performed according to the patient's request. If a patient want to be sedated during surgery, one of the three sedatives (dexmedetomidine, propofol, and midazolam) is administered.

注册库
clinicaltrials.gov
开始日期
2020年4月1日
结束日期
2021年2月28日
最后更新
6年前
研究类型
Observational
性别
All

研究者

责任方
Principal Investigator
主要研究者

Jin-Young Hwang

Associate professor

SMG-SNU Boramae Medical Center

入排标准

入选标准

  • Eldery patients scheduled for spinal anesthesia

排除标准

  • MMSE ≤ 23
  • Hemodynamic unstability
  • Liver disease
  • Renal disease

结局指标

主要结局

EEG frequency bands (alpha, beta, theta, delta, and gamma waves) during spinal anesthesia

时间窗: 30 min after the induction of spinal anesthesia

EEG frequency bands are observed during spinal anesthesia under sedated or unsedated states.

次要结局

  • EEG frequency bands (alpha, beta, theta, delta, and gamma waves) 1 day after surgery(1 day after surgery)
  • Incidence of delirium(For 7 days after surgery.)

相似试验