MedPath

Effect of Etomidate and Propofol on Electroencephalography

Not Applicable
Conditions
General Anesthesia
Interventions
Registration Number
NCT04369014
Lead Sponsor
Air Force Military Medical University, China
Brief Summary

Electroencephalography (EEG) monitoring reflect the brain electro-activity. Different anesthetics may show different changes in EEG during anesthesia. Etomidate and propofol are widely used for general anesthesia. The characteristic changes of these two anesthetics may be different.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
68
Inclusion Criteria
  • Patients scheduled for surgery under general anesthesia
  • Patients provided written informed consent
Exclusion Criteria
  • Patients with history of neurological or psychiatric diseases
  • Patients younger than 18 years old
  • Patients scheduled for surgery involved head
  • Patients with pregnancy or planned for breeding

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
propofolpropofol anesthesia-
etomidateetomidate anesthesia-
Primary Outcome Measures
NameTimeMethod
delta wave deficiency during anesthesiafrom anesthesia induction to extubation of the endotracheal tube, on an average of 2.5 hours
Secondary Outcome Measures
NameTimeMethod
spindle wave deficiency during anesthesiafrom anesthesia induction to extubation of the endotracheal tube, on an average of 2.5 hours
burst suppression during anesthesiafrom anesthesia induction to extubation of the endotracheal tube, on an average of 2.5 hours

Trial Locations

Locations (1)

Xijing hospital

🇨🇳

Xi'an, Shaanxi, China

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