Utility of Thoracic Ultrasound in Patients With Acute Pancreatitis as a Prognostic Tool of Respiratory Dysfunction and Severity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 49
- 试验地点
- 1
- 主要终点
- B-type lines on thoracic point-of-care ultrasound in patients with acute pancreatitis
研究概览
简要总结
Authors design a prospective, longitudinal, descriptive study to identify the findings of thoracic point-of-care ultrasound in patients with acute pancreatitis. Patients will be included in the study since August through December 2019, admitted to the University Hospital, "Dr. José E. González", Universidad Autonoma de Nuevo León. These patients will undergo a pulmonary and vena cava ultrasound at admission, at 24 and 48 hours. The authors will describe findings of pulmonary ultrasound and their correlation with severity in patients with acute pancreatitis of all etiologies. The authors will analyze variables such Systemic inflammatory response syndrome, severity according to the revised Atlanta criteria (2012), and systemic complications.
详细描述
Acute pancreatitis has been described as the most common cause of pancreatic disease with a global incidence of 33-74 per 100.000 people and a mortality of 1-16 per 100.000. Hydration with the purpose of preventing hypovolemia and hypoperfusion of organs is the cornerstone of initial disease management. "Aggressive" hydration, has been based on animal models and observational data from clinical studies, and has been associated with respiratory complications, compartment syndrome, sepsis, and mortality. Nowadays pulmonary ultrasound has been used in a wide array of clinical settings such as intensive care unit, emergency medicine, and nephrology. It has been a standardized tool in internal and pulmonary medicine.
Authors design a prospective, longitudinal, descriptive study to identify the findings of thoracic point-of-care ultrasound in patients with acute pancreatitis. Patients will be included in the study since August through December 2019, admitted to the University Hospital, "Dr. José E. González", Universidad Autonoma de Nuevo León.
OBJECTIVES
- Primary objective:
Describe findings of pulmonary ultrasound and their correlation with severity in patients with acute pancreatitis of all etiologies. The authors will analyze variables such Systemic inflammatory response syndrome, severity according to the revised Atlanta criteria (2012), and systemic complications. 2. Secondary objectives:
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with diagnosis of acute pancreatitis by means of clinical presentation, laboratory results and/or imaging.
- •Both genders.
- •All etiologies of pancreatitis.
- •Ages above 18.
排除标准
- •History of acute pancreatitis in prior 12 months.
- •Patients with referrals from other institutions.
- •Patients with other chronic comorbidities such as renal or cardiac insufficiency.
- •Patients with acute pancreatitis and high suspicion of cholangitis.
- •Patients with acute pancreatitis and acute cholecystitis.
- •Pregnant patients with acute pancreatitis.
- •Patients who decline being part of this study.
结局指标
主要结局
B-type lines on thoracic point-of-care ultrasound in patients with acute pancreatitis
时间窗: 48 hours
The number of B-type lines measured by thoracic point-of-care ultrasound in patients with acute pancreatitis.
次要结局
- Diameter of inferior vena cava on thoracic point-of-care ultrasound in patients with acute pancreatitis.(48 hours)
- B-type lines and Atlanta score in patients with acute pancreatitis(48 hours)
- Inferior vena cava diameter and Atlanta score in patients with acute pancreatitis(48 hours)
- Inferior vena cava diameter and 48 hours mortality in patients with acute pancreatitis(7 days)
研究者
Dr. med. Hector Eloy Tamez Perez
Clinical Professor
Hospital Universitario Dr. Jose E. Gonzalez