ARTEMIS Synovial Markers in Arthritis Childhood
Not Applicable
Completed
- Conditions
- Septic ArthritisJuvenile Idiopathic Arthritis
- Registration Number
- NCT02505828
- Lead Sponsor
- University Hospital, Montpellier
- Brief Summary
The aim of this study is to find markers that could differentiate infectious and inflammatory arthritis. The investigators want to find markers by differential analysis by compare synovial fluids of septic and inflammatory arthritis. The investigators will use for this analysis, proteomics, cytokine dosage and monocyte typing by flow cytometry analysis. The investigators will use one marker or a score with biological and clinical data to discriminate arthritis of infectious and inflammatory etiology.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- Septic arthritis with bacteriological identification
- Juvenile idiopathic arthritis beyond the ILAR definition
- Having acute arthritis requiring an articular draining
- Child benefiting from a national insurance scheme
- Collection of the consent of the parents or the legal representative
Exclusion Criteria
- Contraindication in an articular draining: platelet 50 000 / mm3, Rate of prothrombins lower than 70 %, activated partial thromboplastin times (APTT)> 1,5
- Treatment by biotherapy, corticoids or other immuno suppressor in the month preceding the articular draining.
- Treatment by antibiotic begun more than 24 hours before the draining.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Qualitative analysis of new biological markers (proteic, cytokine or cellular) that discriminate inflammatory and infectious arthritis. 1 day Identify blood sampling biomarkers of Arthritis childhood
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hôpital Arnaud de Villeneuve
🇫🇷Montpellier, France
Hôpital Arnaud de Villeneuve🇫🇷Montpellier, France