NCT02505828已完成不适用
ARTEMIS Synovial Markers in Arthritis Childhood
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Qualitative analysis of new biological markers (proteic, cytokine or cellular) that discriminate inflammatory and infectious arthritis.
研究概览
简要总结
The aim of this study is to find markers that could differentiate infectious and inflammatory arthritis. The investigators want to find markers by differential analysis by compare synovial fluids of septic and inflammatory arthritis. The investigators will use for this analysis, proteomics, cytokine dosage and monocyte typing by flow cytometry analysis. The investigators will use one marker or a score with biological and clinical data to discriminate arthritis of infectious and inflammatory etiology.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 6 Months 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Septic arthritis with bacteriological identification
- •Juvenile idiopathic arthritis beyond the ILAR definition
- •Having acute arthritis requiring an articular draining
- •Child benefiting from a national insurance scheme
- •Collection of the consent of the parents or the legal representative
排除标准
- •Contraindication in an articular draining: platelet 50 000 / mm3, Rate of prothrombins lower than 70 %, activated partial thromboplastin times (APTT)> 1,5
- •Treatment by biotherapy, corticoids or other immuno suppressor in the month preceding the articular draining.
- •Treatment by antibiotic begun more than 24 hours before the draining.
结局指标
主要结局
Qualitative analysis of new biological markers (proteic, cytokine or cellular) that discriminate inflammatory and infectious arthritis.
时间窗: 1 day
Identify blood sampling biomarkers of Arthritis childhood
次要结局
未报告次要终点
研究者
研究点 (2)
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