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Clinical Trials/NCT05954351
NCT05954351
Completed
Not Applicable

PRactice of Ventilation and Adjunctive Therapies in COVID-19 Patients; What is the Optimal Ventilation Strategy in Critically Ill COVID-19 Patients, in Particular PEEP and the Moment of Switch to Pressure Support?

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)1 site in 1 country2,465 target enrollmentMay 1, 2022
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ConditionsCOVID-19 Acute Respiratory Distress Syndrome

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
COVID-19 Acute Respiratory Distress Syndrome
Sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Enrollment
2465
Locations
1
Primary Endpoint
ICU mortality
Status
Completed
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

PRactice of Ventilation and Adjunctive Therapies in COVID-19 Patients. An observational study of ventilation practice and adjunctive therapies in critically ill, invasively ventilated COVID-19 patients during the first and second surge of COVID-19 in the Netherlands.

Registry
clinicaltrials.gov
Start Date
May 1, 2022
End Date
July 1, 2023
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Prof. Dr. Marcus J. Schultz

Professor Dr. Marcus J. Schultz

Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)

Eligibility Criteria

Inclusion Criteria

  • •receiving invasive ventilation or high-flow nasal oxygen for COVID-19 for SARS-CoV-2
  • •admitted to one of the ICUs of the participating hospitals

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

ICU mortality

Time Frame: 90 days from inclusion

Secondary Outcomes

  • 28-day ventilator free days(90 days from inclusion)
  • Duration of ventilation(90 days from inclusion)
  • 28-day, 90-day mortality(90 days from inclusion)
  • ICU and hospital length of stay(90 days from inclusion)

Study Sites (1)

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