Management Through Non-invasive Ventilatory Support of Patients Showing an Acute Respiratory Failure Related to COVID-19 in Non-intensive Wards
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 909
- 试验地点
- 34
- 主要终点
- The number of patients treated with non-invasive ventilation devices.
研究概览
简要总结
Prospective, observational, multicenter study aiming to evaluate the number of COVID-19 pneumonia related patients treated with non-invasive ventilatory support outside the intensive care unit.
In addition, the study aims to obtain information related to the clinical characteristics and hospital results of these patients.
详细描述
In February 2020, the first case of transmission of the syndrome, indicated as COVID-19, was reported in Italy. Unfortunately, during March 2020, the syndrome spread rapidly throughout the country, affecting tens of thousands of patients, including several thousands have requested hospitalization and some hospitalization in intensive care, putting a strain on the entire regional health system.
Patients that present intermediate severity of the infection are often treated with non-invasive ventilatory support which includes high-flow nasal cannulas (HFNC), non-invasive ventilation (NIV), continuous positive airway pressure (CPAP) through face mask or helmet (helmet).
The exponential growth in the number of patients has made the massive use of these devices necessary even outside the intensive or semi-intensive wards where they are traditionally used.
Epidemiological knowledge regarding the type of patients treated with this strategy and the outcome of these patients are limited, but very important in a context of emergency.
Thus, the objective of this prospective multicenter study is to evaluate the number of patients with COVID-19 related pneumonia, treated with non-invasive ventilatory support outside the intensive care unit and to evaluate the clinical characteristics and hospital outcomes of these patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age> = 18 years
- •Diagnosis of COVID-related pneumonia requiring non-invasive ventilatory support (high-flow nasal cannula, and / or non-invasive ventilation and / or CPAP)
排除标准
- •Explicit refusal to participate in the study
结局指标
主要结局
The number of patients treated with non-invasive ventilation devices.
时间窗: Until patient discharge from the hospital (approximately 5 months)
The first purpose of the study is to evaluate the number of COVID-19 related pneumonia patients treated with devices for non-invasive ventilation outside intensive care units.
次要结局
- Incidence of organ failure(Until patient discharge from the hospital (approximately 5 months))
- Incidence of patients requiring mechanical ventilation(Until patient discharge from the hospital (approximately 5 months))
- Duration of hospitalization(Until patient discharge from the hospital (approximately 5 months))
- Clinical outcome at hospital discharge(Until patient discharge from the hospital (approximately 5 months))