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Clinical Trials/NCT05130229
NCT05130229
Completed
N/A

Community Partnership for Healthy Sleep: Sleep Well, Bee Well Part 2

Yale University2 sites in 1 country98 target enrollmentMarch 8, 2022
ConditionsPediatric Sleep

Overview

Phase
N/A
Intervention
Not specified
Conditions
Pediatric Sleep
Sponsor
Yale University
Enrollment
98
Locations
2
Primary Endpoint
Change in Bedtime Variability
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Using a pragmatic cluster randomized trial, this study aims to examine the feasibility, and acceptability of a 3-week behavioral sleep intervention, Sleep Well, Bee Well (SWBW), and to test the preliminary efficacy of SWBW compared to a wait-list control with children ages 1-2.5 years old at two Early Head Start (EHS) centers on toddler sleep characteristics and parent wellbeing.

Detailed Description

The first phase of this study is under another study (please see NCT03045874). For this study (Phase II), a pilot pragmatic cluster randomized trial to test the feasibility and preliminary efficacy of SWBW in improving sleep health in children ages 1-2.5 years attending two Early Head Start (EHS) programs will be studied. A total of 44 families of 1-2.5 year-old healthy children and EHS teachers from both childcare centers will be enrolled. The program teaches early childhood educators about healthy sleep for young children and will train them to be confident facilitators of educational conversations about sleep with parents. The following specific aims will be addressed with this study: (1) Determine the feasibility of SWBW among 44 families of 1-2.5-year-old healthy children and EHS teachers from both childcare centers; (1a) refine and standardize the SWBW intervention materials (videos, handouts, activities); (1b) determine the feasibility (acceptability, demand, implementation, practicality, adaptation, integration, expansion, and limited-efficacy testing) of the SWBW intervention, study design and recruitment goals; (2) Evaluate the preliminary efficacy of SWBW in 22 intervention and 22 wait-list control parent-child dyads on (2a) toddlers' sleep health (duration, timing, continuity), bedtime routines and parent and EHS teacher sleep knowledge and (2b) toddler's social-emotional health, bedtime routines, parent well-being and parent-teacher engagement. The results from this pilot study will provide support for a future larger-scale cluster-randomized trial that will be fully powered to test the effects of the SWBW program in multiple EHS programs enrolled in the New England Head Start Association. Parent questionnaires and sleep characteristics of children (actigraphy and parent report) will be collected at three timepoints- Time 1, 2, and 3. Time 1 is the first Baseline Data Collection for the Waitlist Control Group and Intervention Group, and these data will be collected prior to either group starting the 3-week SWBW intervention. Between Time 1 and Time 2, the Intervention Group will receive the 3-week SWBW intervention at the childcare center. Time 2 data collection for both groups will occur during the week following the completion of the intervention received by the Intervention Group. Time 2 data will serve as post-intervention data for the Intervention Group. Time 2 data will also be compared to the first baseline data collected during Time 1 to account for the Waitlist Control Group's waiting time and be used as secondary baseline pre-intervention data for the Waitlist Control Group. Lastly, Time 3 is the Post-Intervention Data Collection for the Waitlist Control Group and will be examined to assess the sustainability of the intervention in the Intervention Group.

Registry
clinicaltrials.gov
Start Date
March 8, 2022
End Date
October 31, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Change in Bedtime Variability

Time Frame: 21 days

Night-to-night variability of bedtime will be calculated using a series of successive differences created by calculating the differences among adjacent observations within the same subject from the Actiwatch 2 data at Time 1, 2, and 3. The mean squared successive differences can be used to compute the MSSD that is considered to be an index of variability/instability. The investigators hypothesize that SWBW will improve toddlers' objectively measured bedtime variability. Actigraphs are manually reviewed with sleep diaries for confirmation and scoring of variables is done in Actiware software then processed in R and submitted to statistician for calculation.

Change in Children's Sleep Duration Variability

Time Frame: 21 days

Night-to-night variability of sleep duration will be calculated using a series of successive differences created by calculating the differences among adjacent observations within the same subject from the Actiwatch 2 data at Time 1, 2, and 3. The mean squared successive differences can be used to compute the MSSD that is considered to be an index of variability/instability. The investigators hypothesize that SWBW will improve toddlers' objectively measured sleep duration variability. Actigraphs are manually reviewed with sleep diaries for confirmation and scoring of variables is done in Actiware software then processed in R and submitted to statistician for calculation.

Change in Parent reported sleep characteristics

Time Frame: 21 days

Parent reported sleep characteristics will be measured with the Brief Infant Sleep Questionnaire-Revised (BISQ-R) at Time 1, 2, and 3. Each BISQ-R subscale and total score are scaled from 0 to 100. The BISQ-R has been validated against sleep diaries and actigraphy to elicit parent reports of children's sleep patterns (daytime and nocturnal sleep duration, frequency of awakening, sleep latency), sleep habits \[sleeping arrangements, parent-child interactions about sleep (e.g., bedtime behaviors, behaviors related to nocturnal awakenings)\], sleep difficulty (i.e., bedtime resistance, nocturnal awakenings, and snoring, a risk factor for sleep apnea\]. Approximate time to complete: 10 minutes. The investigators anticipate an improvement in the total score of the parent-reported sleep characteristics after receiving the SWBW intervention.

Change in Children's bedtime

Time Frame: 21 days

The bedtime sleep characteristics will be measured with the Respironics Actiwatch AW2, an accelerometer placed on the toddler's ankle. Reliability for actigraphy in toddlers ranges from .67-.85 when measuring sleep duration. The toddlers will wear the water resistant Actiwatch 2 for seven 24-hour periods at Time 1, 2, and 3. The investigators hypothesize that SWBW will improve toddlers' objectively measured bedtime (goal: bedtime before 9:00PM or at least 45 minutes earlier from baseline). Actigraphs are manually reviewed with sleep diaries for confirmation and scoring of variables is done in Actiware software then processed in R and submitted to statistician for calculation.

Change in Children's sleep duration

Time Frame: 21 days

The sleep characteristic of sleep duration will be measured with the Respironics Actiwatch AW2, an accelerometer placed on the ankle of the toddlers. Reliability for actigraphy in toddlers ranges from .67-.85 when measuring sleep duration. The toddler will wear the water resistant Actiwatch 2 for seven 24-hour periods at Time 1, 2, and 3. The investigators hypothesize that toddler's sleep duration will increase by 45 minutes after receiving the SWBW intervention. Actigraphs are manually reviewed with sleep diaries for confirmation and scoring of variables is done in Actiware software then processed in R and submitted to statistician for calculation.

Change in Bedtime Routine

Time Frame: 12 days

Data on the number of vocalizations and level of noise will be collected using the Language Environment Analysis (LENA) recorder and software that measures frequency of vocalization/verbalizations and conversational turns in children. The LENA device will be worn inside of a vest provided to each child that will be worn on top of the children's clothing. Digital audio recordings will be collected for four days at Time 1, 2, and 3 while the child is wearing the actigraph. Software algorithms parse the continuous audio stream into discrete, variable-length segments that are matched to pre-defined sound models, separating speech-related sounds from environmental and other sounds to compute count estimates of adult words, child vocalizations, conversational turns, and decibel levels.

Change in Children's Bedtime Routine

Time Frame: 21 days

Parental Interactive Bedtime Behavior Scale (PIBBS) is a 19-item Likert-type parent questionnaire that measures the interactive behaviors caregivers use with their children at bedtime. A total score is calculated as percentage. Approximate time to complete: 5 minutes. The survey will be collected at Time 1, 2, and 3. This survey will be used to generate hypotheses for future clinical trials with a larger sample size. The investigators anticipate that parental interactive bedtime behaviors will improve upon completion of the SWBW intervention.

Secondary Outcomes

  • Change in Depressive symptoms among parents(21 days)
  • Change in Self-report of parental self-efficacy(21 days)
  • Change in Toddler social-emotional health(21 days)
  • Change in Parenting stress(21 days)
  • Change in Parental knowledge and beliefs about children's sleep(21 days)

Study Sites (2)

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