Prognosis of Right Ventricular Dysfunction Assessed by Speckle Tracking in Postoperative Thoracic Surgery: a Pilot Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Right Ventricle
- Sponsor
- Centre Hospitalier Universitaire, Amiens
- Enrollment
- 164
- Locations
- 1
- Primary Endpoint
- occurrence of a major cardiovascular event (MACE)
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
In postoperative thoracic surgery (lobe resection, pneumonectomy or wedge resection), cardiovascular complications are the most frequent (10 to 15%) with a significant morbi-mortality rate. Right ventricular (RV) dysfunction is a complication that can be multifactorial in post thoracic surgery. The RV longitudinal shortening fraction (RV-LSF) is a new 2D-STE parameters able to more accurately detect patients with RV dysfunction compared to conventional echocardiographic parameters.
This project is a single-center, prospective, interventional study of patients hospitalized at the Amiens University Hospital for scheduled thoracic surgery. TTE is performed preoperatively, at day 2 and day 15 following the thoracic surgery. Echocardiographic parameters will be measured by an echocardiographic expert in offline with a dedicated software. MACE criteria will be collected at day 2, day 15 and day-30 following the thoracic surgery.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adult patient (\>18 years)
- •Patient hospitalized at the Amiens University Hospital for scheduled thoracic surgery (lobectomy, pneumonectomy, wedge resection).
- •Surgery by thoracotomy or video-assisted thoracic surgery
- •Information of the patient and collection of his non-opposition
Exclusion Criteria
- •Patient with poor echogenicity on TTE not allowing evaluation of 2D-STE or conventional parameters of the RV.
- •Patient with a rapid supraventricular rhythm disorder (HR \> 100) at the time of TTE
- •Patient under mechanical ventilation
- •Patient under extracorporeal membrane oxygenation
- •Patients under guardianship or legal protection
- •Patients whose clinical condition does not allow for their non-opposition
- •Pregnant women
Outcomes
Primary Outcomes
occurrence of a major cardiovascular event (MACE)
Time Frame: day 30
MACE is a composite criteria. MACES criteria is defined as the occurrence of at least one of the following events: A cardiovascular death or a documented supraventricular tachycardia (atrial fibrillation and/or flutter) of duration \> 30 seconds or, an acute myocardial infarction or, an hospitalization for a right ventricular failure or, an hospitalization for a left ventricular failure.
Secondary Outcomes
- Variation of RV systolic function from baseline in patients with MACE(within day 30)
- occurrence of a postoperative complication(at day 30)
- Variation of RV systolic function from baseline in patients without MACE(within day 30)
- Assessment of RV systolic function preoperatively(at day 30)