Right Ventricular Dysfunction Incidence After Major Lung Resection, a Prospective Study.
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Major Lung Resection
- Sponsor
- University Hospital, Montpellier
- Enrollment
- 110
- Locations
- 1
- Primary Endpoint
- Right ventricular dysfunction
- Status
- Terminated
- Last Updated
- 7 years ago
Overview
Brief Summary
This study aims to describe incidence of right ventricular dysfunction after major lung resection with echocardiography criteria.
Detailed Description
Few clinical trial studied the incidence of right ventricular dysfunction after major lung resection and time frame of occurrence. In this prospective observational study the right ventricular function will be mesure with echocardiographic criteria. Echocardiographic exam will be standardised and be realised day before surgery (at the same time that inclusion), day 1, day 2 and day 3 after surgery. In order to assess prognostic value of right dysfunction after lung resection, data as hospitalization stay, complications and survival will be collected at 6 months. Cardiac cycles will be recorded and be analysed by a single observer blind to the clinical finding and other echocardiographic measurements.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Written consent
- •Patient older than 18 years
- •Major lung surgery (pneumonectomy, lobectomy)
Exclusion Criteria
- •Pre-existing pulmonary arteria hypertension
- •Post-operative surgical complication on day 1 to 3 (bleeding, revision surgery)
- •Technical difficulty preventing adequate echocardiographic assessment
- •Patient refusal
Outcomes
Primary Outcomes
Right ventricular dysfunction
Time Frame: 5 days
Without pre-existing pulmonary arteria hypertension, it will be assess with echocardiography criteria : PAPS \> 35mmHg or right ventricular dilatation or right systolic markers abnormalities.
Secondary Outcomes
- Risk factors(5 days)
- Time frame to right ventricular dysfunction(5 days)
- Assessment of 2D strain for right ventricular dysfunctio(5 days)
- Estimate impact of right ventricular dysfunction on patient prognosis.(5 days)