Right Ventricular Dysfunction Incidence After Major Lung Resection, a Prospective Study.
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- Right ventricular dysfunction
研究概览
简要总结
This study aims to describe incidence of right ventricular dysfunction after major lung resection with echocardiography criteria.
详细描述
Few clinical trial studied the incidence of right ventricular dysfunction after major lung resection and time frame of occurrence.
In this prospective observational study the right ventricular function will be mesure with echocardiographic criteria. Echocardiographic exam will be standardised and be realised day before surgery (at the same time that inclusion), day 1, day 2 and day 3 after surgery.
In order to assess prognostic value of right dysfunction after lung resection, data as hospitalization stay, complications and survival will be collected at 6 months.
Cardiac cycles will be recorded and be analysed by a single observer blind to the clinical finding and other echocardiographic measurements.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Written consent
- •Patient older than 18 years
- •Major lung surgery (pneumonectomy, lobectomy)
排除标准
- •Pre-existing pulmonary arteria hypertension
- •Post-operative surgical complication on day 1 to 3 (bleeding, revision surgery)
- •Technical difficulty preventing adequate echocardiographic assessment
- •Patient refusal
结局指标
主要结局
Right ventricular dysfunction
时间窗: 5 days
Without pre-existing pulmonary arteria hypertension, it will be assess with echocardiography criteria : PAPS \> 35mmHg or right ventricular dilatation or right systolic markers abnormalities.
次要结局
- Risk factors(5 days)
- Time frame to right ventricular dysfunction(5 days)
- Assessment of 2D strain for right ventricular dysfunctio(5 days)
- Estimate impact of right ventricular dysfunction on patient prognosis.(5 days)