Influence of Obesity and Gastric Bypass on Medication Absorption: Prospective Follow-up of Patients
试验速览
- 阶段
- 不适用
- 发起方
- KU Leuven
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Medication use
研究概览
简要总结
Patients who have scheduled a gastric bypass (RYGB) in UZ Leuven, will be questioned preoperatively and one, three, six and twelve months after gastric bypass surgery. The purpose of this study is to explore current practice regarding the use of medication and medication counseling after RYGB and to examine the changes in dietary pattern before and after RYGB.
详细描述
Target group: patients who have scheduled a gastric bypass in UZ Leuven. Patients will be questioned preoperatively and one, three, six and twelve months after gastric bypass surgery. Each assessment will be performed during a routine consultation.
The following aspects will be investigated:
- Medication The investigators have composed a questionnaire to examine which drugs the patients use, adherence, information received about medication and from whom,...
- Clinical parameters Every consultation, concentrations of hemoglobin, iron, hepcidin, vitamin B12,.... and a 24h urine collection to determine calcium excretion will be collected.
- Dietary intake The investigators will ask patients to keep a food record during two non-consecutive days preceding each consultation. In this food record patients have to note all consumed foods and beverages with the right/estimated amounts. This makes it possible to see the changes of the composition of the meals before and after RYGB.
- Body composition
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who have scheduled gastric bypass
- •Use of at least one chronic drug (including contraception)
排除标准
- •Patients who have undergone another form of bariatric surgery before RYGB
结局指标
主要结局
Medication use
时间窗: one year
Patients will be questioned preoperatively and one, three, six and twelve months after gastric bypass surgery. A questionnaire will be used to examine which drugs patients use and to what level they are adherent to treatment recommendations.
次要结局
- Changes in dietary pattern before and after RYGB(one year)
- Medication counseling(one year)