Microbes and Bariatric Surgery
Completed
- Conditions
- Periodontal DiseaseObesityDiabetes
- Registration Number
- NCT01130207
- Lead Sponsor
- State University of New York - Upstate Medical University
- Brief Summary
The investigators will study people who are obese and will be treated by bariatric surgery. The investigators will test the hypothesis that some of the features of obesity are related to the bacteria in the gastro-intestinal tract.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
- Ages 18-65
- Will undergo bariatric surgery for treatment of obesity in Syracuse NY
- Willingness to participate
Exclusion Criteria
- Any previous gastrointestinal surgery
- Use of antibiotics in the previous 3 months
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in microflora after bariatric surgery Six months Specific differences were measured in oral and intestinal bacteria immediately after surgery.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link gut microbiota changes to metabolic improvements post-bariatric surgery in NCT01130207?
How does bariatric surgery-induced microbiome alteration compare to standard-of-care treatments for obesity-related diabetes and periodontal disease?
Which specific gut microbiota biomarkers predict weight loss success and metabolic outcomes after bariatric surgery in obese patients?
What are the potential adverse events associated with gut microbiome modulation via bariatric surgery and how are they managed?
Are there synergistic effects between bariatric surgery microbiome changes and pharmacological interventions for obesity and diabetes management?
Trial Locations
- Locations (1)
Upstate Medical University
🇺🇸Syracuse, New York, United States