The Effect of Bariatric Surgery to Central Sensitization
- Conditions
- Bariatric SurgeryCentral Sensitization
- Registration Number
- NCT03460691
- Lead Sponsor
- Bursa Yüksek İhtisas Education and Research Hospital
- Brief Summary
Nowadays obesity is emerging as a very common health problem. It has been shown in various studies that obesity may be an important risk factor for the onset and progression of knee osteoarthritis (OA). The aim of this study is to determine the effects of bariatric surgery on knee pain, loss of function, quality of life and central sensitization.
- Detailed Description
Weight loss in patients with knee OA reduces pain and provides functional improvement. It has been shown that bariatric surgery combined with diet and exercise changes have positive effects on weight loss, knee pain and function.
Neuropathic pain is a disease that affects the somatosensory system or pain that results in a lesion. It has been reported that neuropathic pain is more frequently seen in patients with high body mass index.
The hyperreactivity of the central nervous system (CNS) plays an important role in the chronic pain of OA patients. It has been shown that CNS becomes hypersensitive in people with chronic OA pain and central sensitization phenomenon plays an important role in pain complaints reported by these patients.
The aim of this study is to determine the effects of bariatric surgery on knee pain, loss of function, quality of life and central sensitization.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 50
- Patients decided to undergo bariatric surgery
- Patients with knee pain more than 3 months.
- Patients with mental impairment,
- Patients with inflammatory rheumatic disease,
- Patients who had previously undergone knee surgery
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method numeric rating scale (NRS) 6 months It is commonly used to measure the severity of the patients' pain. It consists of a line 10 cm. long and marked with numbers from 0 to 10. The patient is asked to mark the point corresponding to the severity of the pain on this line in the range from 0 (no pain) to 10 (most severe pain).
Nottingham Health Profile 6 months for quality of life
Central Sensitization Inventory (CSI) 6 months for central sensitization
Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC) 6 months for function
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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