The Impact of Bariatric Surgery on Estimated Lipidemia in Chinese Obesity Patients: a Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- preoperative of choleaterol
研究概览
简要总结
Obesity and related metabolic diseases have become a chronic disease that is a threat to human health. Bariatric surgery can effectively and long-term reduce excess body weight and relieve related metabolic diseases, including type 2 diabetes. Laparoscopic gastric bypass surgery and laparoscopic sleeve gastrectomy are commonly used in bariatric surgery. Laparoscopic sleeve gastrectomy due to simple operation, good weight loss, and metabolic disease control effect, which is more widely used. However, there are several studies that show an increased chance of gastroesophageal reflux disease after laparoscopic sleeve gastrectomy. Long-term gastroesophageal reflux may lead to Barrett's esophagus or esophageal cancer. Nowadays, the cause of gastroesophageal reflux disease after sleeve gastrectomy is not clear and precautionary measures are not precise.
In this study, prospective randomized controlled trials were conducted to explore the possible change of lipidemia after bariatric surgery and to explore ways to prevent bariatric surgery after bariatric surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •For the choice of surgical approach, numerous studies have shown that BMI ≧ 45, the general choice of gastric bypass surgery, BMI <45, you can choose sleeve gastrectomy. The remission rate for T2DM, sleeve gastrectomy has a good result for young patients with shorter duration. In the investigator's country, the BMI less than 45 is majorities.
排除标准
- 未提供
研究组 & 干预措施
Lipidemia
干预措施: sleeve gastrectomy (Procedure)
Lipidemia
干预措施: gastric bypass (Procedure)
结局指标
主要结局
preoperative of choleaterol
时间窗: Preoperate
choleaterol in ml/dl
Postoperative of choleaterol at 3 months
时间窗: 3 months
choleaterol in ml/dl
Postoperative of choleaterol at 6 months
时间窗: 6 months
choleaterol in ml/dl
Postoperative of choleaterol at 1 year
时间窗: 1 year
choleaterol in ml/dl
次要结局
- Preoperative of triglyceride(Preoperative)
- Postoperative of triglyceride at 3 months(3 months)
- Postoperative of triglyceride at 6 months(6 months)
- Postoperative of triglyceride at 1 year(1 year)
研究者
Jingge Yang
Director of bariatric surgery
First Affiliated Hospital of Jinan University
