跳至主要内容
临床试验/NCT03689803
NCT03689803Unknown不适用

The Impact of Bariatric Surgery on Estimated Lipidemia in Chinese Obesity Patients: a Retrospective Cohort Study

First Affiliated Hospital of Jinan University1 个研究点 分布在 1 个国家目标入组 1,000 人开始时间: 2018年4月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
发起方
入组人数
1,000
试验地点
1
主要终点
preoperative of choleaterol

研究概览

简要总结

Obesity and related metabolic diseases have become a chronic disease that is a threat to human health. Bariatric surgery can effectively and long-term reduce excess body weight and relieve related metabolic diseases, including type 2 diabetes. Laparoscopic gastric bypass surgery and laparoscopic sleeve gastrectomy are commonly used in bariatric surgery. Laparoscopic sleeve gastrectomy due to simple operation, good weight loss, and metabolic disease control effect, which is more widely used. However, there are several studies that show an increased chance of gastroesophageal reflux disease after laparoscopic sleeve gastrectomy. Long-term gastroesophageal reflux may lead to Barrett's esophagus or esophageal cancer. Nowadays, the cause of gastroesophageal reflux disease after sleeve gastrectomy is not clear and precautionary measures are not precise.

In this study, prospective randomized controlled trials were conducted to explore the possible change of lipidemia after bariatric surgery and to explore ways to prevent bariatric surgery after bariatric surgery.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • For the choice of surgical approach, numerous studies have shown that BMI ≧ 45, the general choice of gastric bypass surgery, BMI <45, you can choose sleeve gastrectomy. The remission rate for T2DM, sleeve gastrectomy has a good result for young patients with shorter duration. In the investigator's country, the BMI less than 45 is majorities.

排除标准

  • 未提供

研究组 & 干预措施

Lipidemia

Active Comparator

干预措施: sleeve gastrectomy (Procedure)

Lipidemia

Active Comparator

干预措施: gastric bypass (Procedure)

结局指标

主要结局

preoperative of choleaterol

时间窗: Preoperate

choleaterol in ml/dl

Postoperative of choleaterol at 3 months

时间窗: 3 months

choleaterol in ml/dl

Postoperative of choleaterol at 6 months

时间窗: 6 months

choleaterol in ml/dl

Postoperative of choleaterol at 1 year

时间窗: 1 year

choleaterol in ml/dl

次要结局

  • Preoperative of triglyceride(Preoperative)
  • Postoperative of triglyceride at 3 months(3 months)
  • Postoperative of triglyceride at 6 months(6 months)
  • Postoperative of triglyceride at 1 year(1 year)

研究者

发起方
First Affiliated Hospital of Jinan University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Jingge Yang

Director of bariatric surgery

First Affiliated Hospital of Jinan University

研究点 (1)

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