Effect of Bariatric Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Morbid Obesity
- Sponsor
- Minia University
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- hormonal change
- Last Updated
- 5 years ago
Overview
Brief Summary
Background: Many of the beneficial metabolic effects of bariatric surgery have been attributed to altered peptide hormone profiles, especially involving pancreatic and gut peptides.
Objectives: assess the effects of bariatric procedures (sleeve gastrectomy, minigastric bypass and sleeve gastrectomy with loop bipartition) on GIT hormones. Methods: Prospective randomized study which was carried out in the department of General Surgery, Minia University hospital during the period from February 2018 to February 2019. This study included 3 groups subjected to different operations; each group consisted of 50 patients.
Detailed Description
Prospective randomized study which was carried out in the department of General Surgery, Minia University hospital during the period from February 2018 to February 2019. This study included 3 groups subjected to different operations; each group consisted of 50 patients. Age ranging from 20 to 50 years old and body weight ranging from 100 to 200 Kg, and subjected to laparoscopic sleeve gastrectomy, mini gastric bypass and sleeve gastrectomy with loop bipartition. Each patient was thoroughly evaluated by a multidisciplinary team (Nutritionist, Endocrinologist, Psychologist, and Surgeon) using a standardized protocol. Follow up was done after two weeks and after 2 months.
Investigators
Amr Abdel Hameed El heny
Assistant professor
Minia University
Eligibility Criteria
Inclusion Criteria
- •All morbid obese patients
Exclusion Criteria
- •GIT diseases
Outcomes
Primary Outcomes
hormonal change
Time Frame: one year
GIT hormones (Ghrelin, secretin, PYY, GLP-1)