Prevention of diabetes with a novel butyrate-enriched triglyceride
- Conditions
- ObesitasInsulin resistanceprediabetes10018424
- Registration Number
- NL-OMON56880
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 48
Inclusion Criteria
Male/female
Age 20-70 year
BMI 28-40 kg/m2 (weight in kg / length in m)
One of the following criteria: fasting glucose 5.6-6.9 mmol/l OR postprandial
glucose (2h) 7.8-11.1 mmol/l OR HOMA-IR>2.2
Exclusion Criteria
Cardiovascular, pulmonary, metabolic (including diabetes mellitus),
gastro-intestinal, liver, kidney or auto-immune disease
Malignancy or disease with life expectancy <5 years
Substance abuse (drugs, alcohol)
Weight change >3kg in past 3 months
Pre/pro/antibiotic use past 3 months or during trial
Use of medication interfering with study outcomes
Streneous physical activity (>3h per week)
Diet-restrictions (hypocaloric, vegan, vegetarian)
Pregnancy
Use of laxatives
Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method