The effect of Nitrous Oxide in comparison to Oxygen combined with Fentanyl on the staying time and pain reduction in renal colic patients at Emergency room

Phase 2

• Conditions: renal colic.; Unspecified renal colic

• Registration Number: IRCT2013020512369N1
• Lead Sponsor: Vice chancellor for research, Isfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Inclusion criteria were as follows:
Age>18 yr; Definite diagnosis of renal colic; Stable hemodynamic (PR=60-100? SBP>100? SPO2>90%?RR=8-22); lack of analgesics usage during last 24 hour; absence of these conditions in patients history: asthma, COPD, intestinal obstruction, hypertension, heart failure, history of previous surgery on kidney and urinary tract, peptic ulcer, GI bleeding, previous history of allergy to fentanyl or other analgesic agents, loss of consciousness, head or chest trauma, pneumocephalus, pneumothorax, drug abuse, abdominal tenderness, rebound tenderness or guarding, retard menstruation; Fill the Informed consent form

Patients were excluded if:
The patient hemodynamic becomes unstable during the process of hospitalization; Hypersensitivity reaction to analgesic drugs occurred; The diagnosis were changed during the further investigations

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of hospitalization. Timepoint: at the end of the intervention. Method of measurement: minutes by timer.;Severity of pain. Timepoint: before and 3-, 5-, 10- and 30-minute after the intervention. Method of measurement: visual analogue scale.