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Pathophysiology of cold intolerance in different patient groups

Recruiting
Conditions
Cold Sensitivity
pain during cold
10043739
10005942
10029317
Registration Number
NL-OMON35399
Lead Sponsor
Erasmus MC, Universitair Medisch Centrum Rotterdam
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
90
Inclusion Criteria

minimum age >18, that are being treated in our hospital. All patients will have the pathological cold intolerance according to Ruijs et al., that is, a CISS score higher than 30.

Exclusion Criteria

* Diseases, that influence the vascular system (such as Diabetes and Raynaud),
* Cardiac diseases and use of cardiac pharmacological supplements (a1,2-blockers and β1-blockers).
* Foreign material in the hand of the patient such as metal operation plates.
* Carpal tunnel syndrome
* Previous application of steroid injections if used in the past five years
* History of musculoskeletal medical conditions (e.g. Rheumatoid arthritis, Fibromyalgia)
* use of antihypertensive drugs

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The questionnaire has a minimum score of 0 and a maximum of 100 points. The<br /><br>temperature-sensitive analysis, will compare the temperature in Celsius<br /><br>degrees. The re-warming is given by Q as number of added energy in joules and<br /><br>compared with de patient groups as well as the control group.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>N.V.T</p><br>
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