Impact of obesity on blood vessel response to stress mediated by the hormone angiotensin II
Not Applicable
- Conditions
- ObesityC18.654.726.500
- Registration Number
- RBR-8mxb7w
- Lead Sponsor
- niversidade Federal Fluminense
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Age between 20 and 50 years; both sexes; body mass index between 25 kg.m-2 and 35 kg.min-2; absence of any chronic diseases (hypertension, diabetes, chronic kidney disease, heart failure, among others, except obesity) and musculoskeletal abnormalities; do not practice physical activity regularly (exercise lasting less than 30 minutes three times a week); and do not make regular use of medications such as vitamins or anti-inflammatory drugs.
Exclusion Criteria
Menopausal or postmenopausal women; smokers; athletes.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement in endothelial function assessed by increased flow-mediated dilation before, thirty minutes and sixty minutes after acute mental stress in overweight / obese grade I men and women from a p value less than or equal to 0, 05 in pre and post intervention comparisons
- Secondary Outcome Measures
Name Time Method Differences in the behavior of vascular and oxidative variables in response to mental stress in grade I overweight / obese men and women, from the finding of a p value less than or equal to 0.05 in pre and post intervention comparisons