Constitution of Cerebrospinal Fluid and Blood Database/Specimen in Acute Stage of Subarachnoid Hemorrhage (aSAH) Patients
- Conditions
- Subarachnoid Hemorrhage
- Registration Number
- NCT01292278
- Lead Sponsor
- University of Regensburg
- Brief Summary
Neuropeptide Y (NPY) may play a major role in the pathophysiology of aneurysmal subarachnoid hemorrhage (aSAH). To investigate the correlation of NPY in cerebrospinal fluid (CSF) and blood (serum) and the neurological outcome in the acute stage of aSAH.
- Detailed Description
Evaluation of Neuropeptides in CSF and serum in SAH patients
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
- spontaneous or aneurysmal subarachnoid hemorrhage
Exclusion Criteria
- age younger than 18 years or older than 70 years
- inflammatory disease
- history of former SAH
- no ventricular drainage
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Glasgow Outcome Scale 2011-2016
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link Neuropeptide Y to aneurysmal subarachnoid hemorrhage pathophysiology?
Are there comparative studies on NPY as a biomarker versus other markers in aSAH prognosis?
How does NPY concentration in CSF correlate with neurological outcomes in acute aSAH patients?
What adverse events are associated with elevated Neuropeptide Y levels post-subarachnoid hemorrhage?
What drug targets related to NPY signaling show potential for treating vasospasm in aSAH?
Trial Locations
- Locations (1)
Department of Neurosurgery Medical Center University of Regensburg
🇩🇪Regensburg, Germany
Department of Neurosurgery Medical Center University of Regensburg🇩🇪Regensburg, GermanyKarl-Michael Schebesch, M.D.Principal Investigator