Antibiotics in acute diverticulitis

Phase 3

Completed

• Conditions: Acute diverticulitis; Surgery - Other surgery; Infection - Studies of infection and infectious agents; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12615000249550
• Lead Sponsor: niversity of Auckland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-03-18
• Study Completion: 2019-05-25
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

1.Age > 18 years.
2.Current inpatient under the General Surgery service
3.Diagnosed with uncomplicated acute diverticulitis on CT scan within 24 hours of admission

Exclusion Criteria

1.Pregnancy.
2.Previous allergic reaction with cefuroxime, metronidazole or amoxicillin/clavulanic acid use
3.Steroid or immunomodulator use for more than 5 days prior to presentation
4.Greater than 1 week of regular, non-steroidal anti-inflammatory drug use prior to presentation
5.Inflammatory bowel disease
6.ASA of 4 or greater
7.CT evidence of complicated disease
8.Meets criteria for a diagnosis of SIRS

Study & Design

• Study Type: Interventional
• Study Design: Not specified