Clinical Study for Liangxue Tongyu Prescription on Anti-inflammatory Effect of Intestinal Microflora and Its Metabolite SCFAs in Intracerebral Hemorrhage

Phase 1

• Conditions: Intracerebral Hemorrhage

• Registration Number: ITMCTR1900002596
• Lead Sponsor: anjing Hospital of Chinese Medcine Affiliated to Nanjing University of Chinese Medicine/Nanjing Hospital of Traditional Chinese Medcine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Consistent with the diagnostic criteria of intracerebral hemorrhage.
2. Syndrome differentiation of TCM belongs to the excess syndrome.
3. Hospitalized patients within 72 hours of onset.
4. 6 <= NIHSS <= 21.
5. Aged 18-85 years.
6. Patients who did not use hormones or gastrointestinal motility drugs before the first blood collection.
7. Sign the informed consent.

Exclusion Criteria

1. Patients with transient ischemic attack and cerebral infarction.
2. Subarachnoid hemorrhage and intracerebral hemorrhage caused by hematological diseases, tumors or trauma.
3. Severe aphasia and cognitive impairment occurred after the onset of the disease.
4. Patients with severe organic diseases of digestive system.
5. Allergic constitution.
6. Patients with severe primary diseases such as liver, kidney, hematopoietic system and endocrine system.
7. Pregnant or lactating women or patients who have recently had birth planning.
8. Persons with disabilities prescribed by law (blindness, deafness, dumbness, mental retardation, mental retardation and limb disability caused by other reasons affecting neurological impairment assessors).
9. Suspect or have a history of alcohol or drug abuse, or other situations that, according to the judgement of the researchers, may reduce the likelihood of enrollment or complicate the enrollment.
10. Patients who are participating in other clinical trials or Patients have participated in other drug clinical trials for less than three months.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
IHSS score;Activity of Daily Life Score;Gastrointestinal dysfunction score;Location and volume of cerebral hemorrhage and grading of cerebral edema; Clinical Symptom Score of Intestinal Function;Diagnostic scoring of apoplexy;