Study on the Effect and Mechanism of Liangxuehuayuan Decoction in Increasing Efficacy and Reducing Toxicity in Radiotherapy of Esophageal Cancer

Phase 1

• Conditions: Esophagus Cancer

• Registration Number: ITMCTR2000003250
• Lead Sponsor: Jiangsu Provincial Hospital of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. The patient has a definite pathological and cytological diagnosis;
2. Peripheral white blood cells >= 4.0 x 10^9 / L, hemoglobin >= 90g / L, platelets >= 80 x 10^9 / L before radiotherapy;
3. KPS score >= 60 points, expected survival time> 3 months;
4. Liquid diet;
5. No esophageal perforation or active bleeding;
6. No serious heart, lung, liver and kidney function, coagulation dysfunction;
7. Cases in the experimental group still need to meet the Chinese medicine yin deficiency poison the diagnostic criteria for the syndrome of heat syndrome (prepared by Zhou Zhongying's Chinese Medicine): chest pain, poor sleep, low fever night sweats, or strong heat, thirst, dry stools, red tongue, yellow tongue coating, pulse count or large.

Exclusion Criteria

1. Patients with mental illness or intellectual disability;
2. Poor compliance;
3. Allergic to experimental drugs;
4. At the same time participating in other clinical trials;
5. Combining other serious diseases, such as other tumors or serious infections.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
OS, PFS, RFS and TTP;Cytokines;CR, PR, SD, PD;