Evaluation of Levothyroxin therapy on Oxidant and anti Oxidant level in subclinical hypothyroid patients

Phase 3

• Conditions: subclinical hypothyroidism.; Other specified hypothyroidism; E03.8

• Registration Number: IRCT20121001010980N4
• Lead Sponsor: Endocrinology and Metabolism Research Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 15 June 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

age=17-42
5<=TSH>=10
NORMAL TotalT4

Exclusion Criteria

Smoking
alcohol consumption
Pregnancy and pregnancy intent
Sodium levothyroxine consumption
lipid lowering drugs
Anti hypertensive drugs
Taking vitamin supplements that affect the state of oxidative stress
History of diabetes Mellitus
- History of cardiovascular disease
History of liver disease
History of kidney disease

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Oxidant-Antioxidant balance. Timepoint: before intervention and 12 weeks after levothyroxin therapy. Method of measurement: serum sample.By the method of measuring prooxidant-antioxidant balance.Measurement of light spectrum by Eliza reader.;Hs-CRP. Timepoint: before intervention and 12 weeks after levothyroxin. Method of measurement: serum sample.Immunoturbidometry assay with commercial kit.