Effect of quyushengxin recipe on intestinal microorganism in patients with ulcerative colitis

Not Applicable

Recruiting

Conditions: ulcerative colitis

Registration Number: ITMCTR1900002355

Lead Sponsor: Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of T.C.M

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: Not specified

Inclusion Criteria

Inclusion criteria for normal volunteers:
1) normal healthy without any previous medical history;
2) the defecation law is unobstructed and the fecal material is soft forming;
3) persons aged between 18 and 65 years;
4) good compliance with researchers' observation, voluntary participation, and signing of informed consent.
Ulcerative colitis group inclusion criteria:
1) those with clinical symptoms, colonoscopy and intestinal mucosa biopsy pathological specimens meeting the diagnostic criteria at the same time;
2) persons aged between 18 and 65 years;
3) the activity score of ulcerative colitis evaluated by the modified Mayo scoring system is less than or equal to 10 points;
4) good compliance with researchers' observation, voluntary participation, and signing of informed consent.

Exclusion Criteria

Exclusion criteria for normal volunteers:
1) those who do not meet the inclusion criteria;
2) pregnant or lactating women with allergies.
Ulcerative colitis group exclusion criteria:
1) clinical symptoms, colonoscopy findings, or pathological specimens of intestinal mucosa biopsy fail to meet the diagnostic criteria;
2) pregnant or lactating women, allergic constitution and allergic to the observed drugs;
3) patients with severe primary diseases of cardiovascular, cerebrovascular, liver, kidney and hematopoietic system;
4) patients with intestinal stenosis, intestinal obstruction, intestinal perforation, rectal polyps, toxic colonic dilatation, colon cancer, rectal cancer and anal diseases;Acute fulminant, severe patients;
5) the patient fails to use the medicine as prescribed, and the efficacy cannot be judged or the efficacy is affected by incomplete data.